Drugplain

Zinc Chloride 1 mg/mL

Zinc Chloride · INJECTION · Exela Pharma Sciences,LLC

9 Recalls on Record
Plain English

Zinc Chloride is an intravenous injection used to provide zinc supplementation for patients who cannot get adequate nutrition through eating, such as those receiving long-term intravenous feeding. It helps maintain normal body functions including immune system support and wound healing.

Key Facts

Brand Name
Zinc Chloride
Generic Name
Zinc Chloride
NDC Code (Product)
51754-0102
Manufacturer
Exela Pharma Sciences,LLC
Strength
1 mg/mL
Dosage Form
INJECTION
Route
INTRAVENOUS
Marketing Status
Application #
ANDA212007
Marketing Start
08/27/2021

Recall History

9 Recalls on Record
Class II02/08/2019

McDaniel Life-Line LLC

Unapproved new drug

TerminatedVoluntary: Firm initiated
Class II11/17/2016

Tri-Coast Pharmacy

Lack of Assurance of Sterility

OngoingVoluntary: Firm initiated
Class II06/02/2015

The Compounding Pharmacy of America

Lack of Assurance of Sterility; FDA inspection identified GMP violations potentially impacting product quality and sterility

TerminatedVoluntary: Firm initiated
Class II05/13/2016

Medaus, Inc.

Lack of Assurance of Sterility

TerminatedVoluntary: Firm initiated
Class III04/08/2013

Hi-Tech Pharmacal Co., Inc.

Subpotent; Cetylpyridinum Chloride

TerminatedVoluntary: Firm initiated
Class II01/15/2020

Fusion IV Pharmaceuticals, Inc. dba Axia Pharmaceutical

Lack of Assurance of Sterility

TerminatedVoluntary: Firm initiated
Class II05/21/2012

Franck's Lab Inc., d.b.a. Franck's Compounding Lab

Lack of Assurance of Sterility: Franck's Lab Inc. initiated a recall of all Sterile Human Drugs distributed between 11/21/2011 and 05/21/2012. FDA environmental sampling revealed the presence of microorganisms and fungal growth in the clean room where sterile products were prepared.

TerminatedVoluntary: Firm initiated
Class II07/30/2025

GenoGenix LLC

Lack of Assurance of Sterility

OngoingVoluntary: Firm initiated
Class II05/09/2022

Olympia Compounding Pharmacy dba Olympia Pharmacy

Lack of assurance of sterility.

CompletedVoluntary: Firm initiated

Side Effects Reported to FDA

FDA FAERS database · These are reported events, not confirmed side effects

drug ineffective86 reports
macular degeneration84 reports
nausea58 reports
malaise54 reports
pain53 reports
pyrexia53 reports
weight decreased53 reports
off label use52 reports
paraesthesia oral52 reports
therapeutic product effect incomplete52 reports

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

INDICATIONS AND USAGE Zinc Chloride Injection, USP, 1 mg/mL is indicated for use as a supplement to intravenous solutions given for TPN. Administration helps to maintain zinc serum levels and to prevent depletion of endogenous stores, and subsequent deficiency symptoms.

Dosage & Administration

DOSAGE AND ADMINISTRATION Zinc Chloride Injection, USP contains 1 mg/mL and is administered intravenously only after dilution. The additive should be diluted prior to administration in a volume of fluid not less than 100 mL. For the metabolically stable adult receiving TPN, the suggested intravenous dosage is 2.5 to 4 mg zinc/day (2.5 to 4 mL/day). An additional 2 mg zinc/day (2 mL/day) is suggested for acute catabolic states. For the stable adult with fluid loss from the small bowel, an additional 12.2 mg zinc/liter of small bowel fluid lost (12.2 mL/liter of small bowel fluid lost), or an additional 17.1 mg zinc/kg of stool or ileostomy output (17.1 mL/kg of stool or ileostomy output) is recommended. Frequent monitoring of zinc blood levels is suggested for patients receiving more than the usual maintenance dosage level of zinc. For full term infants and children up to 5 years of age, 100 mcg zinc/kg/day (0.1 mL/kg/day) is recommended. For premature infants (birth weight less than 1500 g) up to 3 kg in body weight, 300 mcg zinc/kg/day (0.3 mL/kg/day) is suggested. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administratio

Warnings

WARNINGS Direct intramuscular or intravenous injection of Zinc Chloride Injection, USP, 1 mg/mL is contraindicated as the acidic pH of the solution (2) may cause considerable tissue irritation. Severe kidney disease may make it necessary to reduce or omit chromium and zinc doses because these elements are primarily eliminated in the urine. WARNING: This product contains aluminum that may be toxic. Aluminum may reach toxic levels with prolonged parenteral administration if kidney function is impaired. Premature neonates are particularly at risk because their kidneys are immature, and they require large amounts of calcium and phosphate solutions, which contain aluminum. Research indicates that patients with impaired kidney function, including premature neonates, who receive parenteral levels of aluminum at greater than 4 to 5 mcg/kg/day accumulate aluminum at levels associated with central nervous system and bone toxicity. Tissue loading may occur at even lower rates of administration.

Contraindications

CONTRAINDICATIONS None known.

Adverse Reactions

ADVERSE REACTIONS None known.

Frequently Asked Questions

What is Zinc Chloride used for?

Zinc Chloride is an intravenous injection used to provide zinc supplementation for patients who cannot get adequate nutrition through eating, such as those receiving long-term intravenous feeding. It helps maintain normal body functions including immune system support and wound healing.

Is Zinc Chloride a controlled substance?

Zinc Chloride is not classified as a controlled substance by the DEA.

What is the generic name for Zinc Chloride?

The generic name for Zinc Chloride is Zinc Chloride. There are 3 other brand versions of Zinc Chloride.

What is the NDC code for Zinc Chloride 1 mg/mL?

The NDC (National Drug Code) for Zinc Chloride 1 mg/mL is 51754-0102, listed by Exela Pharma Sciences,LLC.

Product NDC

51754-0102

Package NDC

51754-0102-4

Other Zinc Chloride Dosages

Not medical advice. Always consult your doctor or pharmacist before making any medication decisions.

Data from openFDA · Public domain (CC0 1.0)