Drugplain

Walgreens Headache Relief Extra Strength 250 mg/1

Acetaminophen 250mg, Aspirin 250mg and Caffeine 65mg · TABLET, COATED · Walgreens

No Recall HistoryCurrently in Shortage
Plain English

This over-the-counter tablet combines acetaminophen, aspirin, and caffeine to relieve headaches and other minor aches and pains. The combination works through multiple pain-relieving mechanisms, with caffeine helping to enhance the effectiveness of the other ingredients.

Key Facts

Brand Name
Walgreens Headache Relief Extra Strength
Generic Name
Acetaminophen 250mg, Aspirin 250mg and Caffeine 65mg
NDC Code (Product)
0363-6693
Manufacturer
Walgreens
Strength
250 mg/1
Dosage Form
TABLET, COATED
Route
ORAL
Marketing Status
Application #
M013
Drug Class
Nonsteroidal Anti-inflammatory Drug [EPC]; Platelet Aggregation Inhibitor [EPC]
Marketing Start
05/01/2026

Recall History

No Recall History

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

Uses Temporarily relieves minor aches and pains due to: ■ headache ■ a cold ■ arthritis ■ muscular aches ■ toothache ■ premenstrual and menstrual cramps

Dosage & Administration

Directions ■ do not use more than directed (see overdose warning) ■ drink a full glass of water with each dose ■ adults and children 12 years and over: take 2 geltabs every 6 hours; not more than 8 geltabs in 24 hours ■ children under 12 years: ask a doctor

Warnings

Warnings Reye's syndrome: Children and teenagers who have or are recovering from chicken pox or flu-like symptoms should not use this product. When using this product, if changes in behavior with nausea and vomiting occur, consult a doctor because these symptoms could be an early sign of Reye's syndrome, a rare but serious illness. Allergy alert: Acetaminophen may cause skin reactions. Symptoms may include: ■ skin reddening ■ blisters ■ rash If a skin reaction occurs, stop use and seek medical help right away. Allergy alert: Aspirin may cause a severe allergic reaction which may include: ■ hives ■ facial swelling ■ asthma (wheezing) ■ shock Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take ■ more than 8 geltabs in 24 hours, which is the maximum daily amount ■ with other drugs containing acetaminophen ■ 3 or more alcoholic drinks every day while using this product Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding. The chance is higher if you ■ are age 60 or older ■ have had stomach ulcers or bleeding problems ■ take a blood thinning (anticoagulant) or steroid drug ■ take other drugs containin

Frequently Asked Questions

What is Walgreens Headache Relief Extra Strength used for?

This over-the-counter tablet combines acetaminophen, aspirin, and caffeine to relieve headaches and other minor aches and pains. The combination works through multiple pain-relieving mechanisms, with caffeine helping to enhance the effectiveness of the other ingredients.

Is Walgreens Headache Relief Extra Strength a controlled substance?

Walgreens Headache Relief Extra Strength is not classified as a controlled substance by the DEA.

What is the generic name for Walgreens Headache Relief Extra Strength?

The generic name for Walgreens Headache Relief Extra Strength is Acetaminophen 250mg, Aspirin 250mg and Caffeine 65mg. There are no other listed brand versions of Acetaminophen 250mg, Aspirin 250mg and Caffeine 65mg.

What is the NDC code for Walgreens Headache Relief Extra Strength 250 mg/1?

The NDC (National Drug Code) for Walgreens Headache Relief Extra Strength 250 mg/1 is 0363-6693, listed by Walgreens.

Product NDC

0363-6693

Package NDC

0363-6693-12

Not medical advice. Always consult your doctor or pharmacist before making any medication decisions.

Data from openFDA · Public domain (CC0 1.0)