Tussin Severe 650 mg/20mL
acetaminophen, dextromethorphan hydrobromide, guaifenesin · SOLUTION · HyVee Inc
Tussin Severe is an over-the-counter liquid medication that combines a pain reliever, cough suppressant, and expectorant to help relieve cough and congestion associated with colds and flu. It works by reducing cough, loosening mucus, and relieving minor aches and fever.
Key Facts
- Brand Name
- Tussin Severe
- Generic Name
- acetaminophen, dextromethorphan hydrobromide, guaifenesin
- NDC Code (Product)
42507-581- Manufacturer
- HyVee Inc
- Strength
- 650 mg/20mL
- Dosage Form
- SOLUTION
- Route
- ORAL
- Marketing Status
- Application #
- M012
- Drug Class
- Expectorant [EPC]
- Marketing Start
- 01/28/2026
Recall History
No Recall HistoryFrequently Asked Questions
What is Tussin Severe used for?
Tussin Severe is an over-the-counter liquid medication that combines a pain reliever, cough suppressant, and expectorant to help relieve cough and congestion associated with colds and flu. It works by reducing cough, loosening mucus, and relieving minor aches and fever.
Is Tussin Severe a controlled substance?
Tussin Severe is not classified as a controlled substance by the DEA.
What is the generic name for Tussin Severe?
The generic name for Tussin Severe is acetaminophen, dextromethorphan hydrobromide, guaifenesin. There are 12 other brand versions of acetaminophen, dextromethorphan hydrobromide, guaifenesin.
What is the NDC code for Tussin Severe 650 mg/20mL?
The NDC (National Drug Code) for Tussin Severe 650 mg/20mL is 42507-581, listed by HyVee Inc.
Other Acetaminophen, Brands
See all →- Mucinex Fast-Max Kickstart Severe Cold and Flu650 mg/20mL72854-138
- DayQuil Severe plus Vicks VapoCool Cold and Flu325 mg/137000-524
- Vicks DayQuil and Vicks NyQuil Severe Cold and Flu37000-814
- Cold Flu Severe325 mg/137808-663
- Medique at Home Decorel Forte325 mg/147682-735
- Medi-First Cough Cold325 mg/147682-835
- equate daytime cold and flu325 mg/15mL49035-476
- dg health tussin650 mg/20mL55910-398
- dg health day time severe cold and flu relief night time severe cold and flu relief55910-643
- tussin severe650 mg/20mL59640-010
Not medical advice. Always consult your doctor or pharmacist before making any medication decisions.
Data from openFDA · Public domain (CC0 1.0)