Drugplain

Travoprost Ophthalmic Solution .04 mg/mL

Travoprost Ophthalmic Solution · SOLUTION/ DROPS · Gland Pharma Limited

4 Recalls on Record
Plain English

Travoprost Ophthalmic Solution is a solution/ drops containing travoprost ophthalmic solution at .04 mg/mL, taken ophthalmic. Manufactured by Gland Pharma Limited.

Key Facts

Brand Name
Travoprost Ophthalmic Solution
Generic Name
Travoprost Ophthalmic Solution
NDC Code (Product)
68083-601
Manufacturer
Gland Pharma Limited
Strength
.04 mg/mL
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Marketing Status
Application #
ANDA218159
Drug Class
Prostaglandin Analog [EPC]
Marketing Start
07/12/2024

Recall History

4 Recalls on Record
Class II10/05/2016

Par Pharmaceutical, Inc.

Lack of Assurance of Sterility; damage to the internal portion of the dropper tip portion of the container

TerminatedVoluntary: Firm initiated
Class II04/01/2022

Mylan Pharmaceuticals Inc

Subpotent Drug and Failed Impurities/Degradation Specifications: low out-of-specification results obtained for assay and high out-of-specification results for related substance impurities/degradation during routine stability testing.

TerminatedVoluntary: Firm initiated
Class II05/25/2023

Golden State Medical Supply Inc.

Lack of Assurance of Sterility: Tamper Evidence Seal is missing on secondary container.

TerminatedVoluntary: Firm initiated
Class II03/15/2021

Cardinal Health Inc.

CGMP Deviations: Intermittent exposure to temperature excursion during storage.

TerminatedVoluntary: Firm initiated

Side Effects Reported to FDA

FDA FAERS database · These are reported events, not confirmed side effects

pneumonia3 reports
headache2 reports
ocular hyperaemia2 reports
pain2 reports
arthritis1 reports
blood pressure increased1 reports
bruxism1 reports
cardiac failure chronic1 reports
condition aggravated1 reports
depression1 reports

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

1 INDICATIONS AND USAGE Travoprost ophthalmic solution (ionic buffered solution) 0.004% is indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. Travoprost ophthalmic solution (ionic buffered solution) is a prostaglandin analog indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. ( 1 )

Dosage & Administration

2 DOSAGE AND ADMINISTRATION The recommended dosage is one drop in the affected eye(s) once daily in the evening. Travoprost ophthalmic solution (ionic buffered solution) should not be administered more than once daily since it has been shown that more frequent administration of prostaglandin analogs may decrease the IOP lowering effect. Reduction of the IOP starts approximately 2 hours after the first administration with maximum effect reached after 12 hours. Travoprost ophthalmic solution (ionic buffered solution) may be used concomitantly with other topical ophthalmic drug products to lower IOP. If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart. One drop in the affected eye(s) once daily in the evening. ( 2 )

Contraindications

4 CONTRAINDICATIONS None. None ( 4 )

Adverse Reactions

6 ADVERSE REACTIONS Most common adverse reaction (30% to 50%) is conjunctival hyperemia. ( 6.1 ) To report SUSPECTED ADVERSE REACTIONS, contact Viatris at 1-877-446-3679 (1-877-4-INFO-RX) or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. The most common adverse reaction observed in controlled clinical trials with travoprost ophthalmic solution 0.004% was ocular hyperemia, which was reported in 30% to 50% of patients. Up to 3% of patients discontinued therapy due to conjunctival hyperemia. Ocular adverse reactions reported at an incidence of 5% to 10% in these clinical trials included decreased visual acuity, eye discomfort, foreign body sensation, pain, and pruritus. Ocular adverse reactions reported at an incidence of 1% to 4% in clinical trials with travoprost ophthalmic solution 0.004% included abnormal vision, blepharitis, blurred vision, cataract, conjunctivitis, corneal staining, dry ey

Frequently Asked Questions

What is Travoprost Ophthalmic Solution used for?

Travoprost Ophthalmic Solution contains Travoprost Ophthalmic Solution. It is a solution/ drops taken ophthalmic. Consult your doctor for specific uses.

Is Travoprost Ophthalmic Solution a controlled substance?

Travoprost Ophthalmic Solution is not classified as a controlled substance by the DEA.

What is the generic name for Travoprost Ophthalmic Solution?

The generic name for Travoprost Ophthalmic Solution is Travoprost Ophthalmic Solution. There are 6 other brand versions of Travoprost Ophthalmic Solution.

What is the NDC code for Travoprost Ophthalmic Solution .04 mg/mL?

The NDC (National Drug Code) for Travoprost Ophthalmic Solution .04 mg/mL is 68083-601, listed by Gland Pharma Limited.