Drugplain

Tobramycin Ophthalmic Solution 3 mg/mL

Tobramycin Ophthalmic Solution · SOLUTION/ DROPS · Alembic Pharmaceuticals Limited

3 Recalls on RecordCurrently in Shortage
Plain English

Tobramycin Ophthalmic Solution is a solution/ drops containing tobramycin ophthalmic solution at 3 mg/mL, taken ophthalmic. Manufactured by Alembic Pharmaceuticals Limited.

Key Facts

Brand Name
Tobramycin Ophthalmic Solution
Generic Name
Tobramycin Ophthalmic Solution
NDC Code (Product)
46708-518
Manufacturer
Alembic Pharmaceuticals Limited
Strength
3 mg/mL
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Marketing Status
Application #
ANDA211847
Drug Class
Aminoglycoside Antibacterial [EPC]
Marketing Start
04/19/2019

Recall History

3 Recalls on Record
Class II10/13/2022

Akorn, Inc.

CGMP Deviations:

OngoingVoluntary: Firm initiated
Class II10/13/2022

Akorn, Inc.

CGMP Deviations:

OngoingVoluntary: Firm initiated
Class II04/26/2023

Akorn, Inc.

CGMP Deviations: Firm went out of business and could no longer continue stability studies.

OngoingVoluntary: Firm initiated

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

INDICATIONS AND USAGE Tobramycin ophthalmic solution, 0.3 % is a topical antibiotic indicated in the treatment of external infections of the eye and its adnexa caused by susceptible bacteria. Appropriate monitoring of bacterial response to topical antibiotic therapy should accompany the use of tobramycin ophthalmic solution. Clinical studies have shown tobramycin to be safe and effective for use in children.

Dosage & Administration

DOSAGE AND ADMINISTRATION In mild to moderate disease, instill 1 or 2 drops into the affected eye(s) every 4 hours. In severe infections, instill 2 drops into the eye(s) hourly until improvement, following which treatment should be reduced prior to discontinuation.

Warnings

WARNINGS FOR TOPICAL OPHTHALMIC USE. NOT FOR INJECTION INTO THE EYE. Sensitivity to topically applied aminoglycosides may occur in some patients. Severity of hypersensitivity reactions may vary from local effects to generalized reactions such as erythema, itching, urticaria, skin rash, anaphylaxis, anaphylactoid reactions, or bullous reactions. If a sensitivity reaction to Tobramycin ophthalmic solution, 0.3% occurs, discontinue use.

Contraindications

CONTRAINDICATIONS Tobramycin ophthalmic solution, 0.3% is contraindicated in patients with known hypersensitivity to any of its components.

Adverse Reactions

ADVERSE REACTIONS The most frequent adverse reactions to Tobramycin ophthalmic solution, 0.3% are hypersensitivity and localized ocular toxicity, including lid itching and swelling, and conjunctival erythema. These reactions occur in less than three of 100 patients treated with Tobramycin ophthalmic solution. Postmarketing Experience: Additional adverse reactions identified from post-marketing use include anaphylactic reaction, Stevens-Johnson syndrome, and erythema multiforme. The following additional adverse reactions have been reported with systemic aminoglycosides: Neurotoxicity, ototoxicity and nephrotoxicity have occurred in patients receiving systemic aminoglycoside therapy. Aminoglycosides may aggravate muscle weakness in patients with known or suspected neuromuscular disorders, such as myasthenia gravis or Parkinson’s disease, because of their potential effect on neuromuscular function.

Frequently Asked Questions

What is Tobramycin Ophthalmic Solution used for?

Tobramycin Ophthalmic Solution contains Tobramycin Ophthalmic Solution. It is a solution/ drops taken ophthalmic. Consult your doctor for specific uses.

Is Tobramycin Ophthalmic Solution a controlled substance?

Tobramycin Ophthalmic Solution is not classified as a controlled substance by the DEA.

What is the generic name for Tobramycin Ophthalmic Solution?

The generic name for Tobramycin Ophthalmic Solution is Tobramycin Ophthalmic Solution. There are no other listed brand versions of Tobramycin Ophthalmic Solution.

What is the NDC code for Tobramycin Ophthalmic Solution 3 mg/mL?

The NDC (National Drug Code) for Tobramycin Ophthalmic Solution 3 mg/mL is 46708-518, listed by Alembic Pharmaceuticals Limited.

Product NDC

46708-518

Package NDC

46708-518-05

Other Tobramycin Ophthalmic Solution Dosages

Not medical advice. Always consult your doctor or pharmacist before making any medication decisions.

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