Drugplain

Systane 4 mg/mL

polyethylene glycol and propylene glycol · SOLUTION/ DROPS · Alcon Research Ltd

6 Recalls on Record
Plain English

Systane is a solution/ drops containing polyethylene glycol and propylene glycol at 4 mg/mL, taken ophthalmic. Manufactured by Alcon Research Ltd.

Key Facts

Brand Name
Systane
Generic Name
polyethylene glycol and propylene glycol
NDC Code (Product)
0065-0431
Manufacturer
Alcon Research Ltd
Strength
4 mg/mL
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Marketing Status
Application #
M018
Marketing Start
10/30/2015

Recall History

6 Recalls on Record
Class II06/29/2022

Mckesson Medical-Surgical Inc. Corporate Office

CGMP Deviations: products were stored outside the drug label specifications.

TerminatedVoluntary: Firm initiated
Class I12/18/2024

Alcon Research LLC

Non-Sterility

OngoingVoluntary: Firm initiated
Class II06/23/2022

Family Dollar Stores, Llc.

CGMP Deviations: product held outside appropriate storage temperature conditions.

OngoingVoluntary: Firm initiated
Class II04/21/2026

Alcon Research LLC

Lack of Assurance of Sterility: Due to FDA inspection observations that it believes may impact product quality.

OngoingVoluntary: Firm initiated
Class II06/29/2022

Mckesson Medical-Surgical Inc. Corporate Office

CGMP Deviations: products were stored outside the drug label specifications.

TerminatedVoluntary: Firm initiated
Class II06/29/2022

Mckesson Medical-Surgical Inc. Corporate Office

CGMP Deviations: products were stored outside the drug label specifications.

TerminatedVoluntary: Firm initiated

Side Effects Reported to FDA

FDA FAERS database · These are reported events, not confirmed side effects

eye irritation1,588 reports
vision blurred1,014 reports
eye pain834 reports
drug ineffective770 reports
ocular hyperaemia692 reports
dry eye608 reports
eye pruritus493 reports
product quality issue437 reports
foreign body sensation in eyes394 reports
nausea335 reports

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

Uses for the temporary relief of burning and irritation due to dryness of the eye for the temporary relief of discomfort due to minor irritations of the eye or to exposure to wind or sun

Dosage & Administration

Directions shake well before using put 1 or 2 drops in the affected eye(s) as needed

Warnings

Warnings For external use only

Frequently Asked Questions

What is Systane used for?

Systane contains polyethylene glycol and propylene glycol. It is a solution/ drops taken ophthalmic. Consult your doctor for specific uses.

Is Systane a controlled substance?

Systane is not classified as a controlled substance by the DEA.

What is the generic name for Systane?

The generic name for Systane is polyethylene glycol and propylene glycol. There are 1 other brand versions of polyethylene glycol and propylene glycol.

What is the NDC code for Systane 4 mg/mL?

The NDC (National Drug Code) for Systane 4 mg/mL is 0065-0431, listed by Alcon Research Ltd.

Product NDC

0065-0431

Package NDC

0065-0431-33

Not medical advice. Always consult your doctor or pharmacist before making any medication decisions.

Data from openFDA · Public domain (CC0 1.0)