Succinylcholine Chloride 200 mg/10mL
Succinylcholine Chloride · INJECTION · Micro Labs Limited
Succinylcholine Chloride is a injection containing succinylcholine chloride at 200 mg/10mL, taken intramuscular. Manufactured by Micro Labs Limited.
Key Facts
- Brand Name
- Succinylcholine Chloride
- Generic Name
- Succinylcholine Chloride
- NDC Code (Product)
42571-371- Manufacturer
- Micro Labs Limited
- Strength
- 200 mg/10mL
- Dosage Form
- INJECTION
- Route
- INTRAMUSCULAR, INTRAVENOUS
- Marketing Status
- Application #
- ANDA214879
- Marketing Start
- 03/01/2021
Recall History
Advanced Pharma Inc.
Labeling: Not Elsewhere Classified: Products may contain synthetic latex and/or natural latex.
BayCare Integrated Service Center, LLC /dba BayCare Central Pharmacy
Lack of sterility assurance
PharMedium Services, Llc
Lack of Assurance of Sterility; media fill failure at manufacturer
Nephron Pharmaceuticals Corporation dba Nephron Sterile Compounding Center
Incorrect labeling: Incorrect or missing lot and/or exp date
Nephron Sterile Compounding Center LLC
Lack of Assurance of Sterility
Advanced Pharma Inc.
Lack of Assurance of Sterility
PharMEDium Services, LLC
Firm is recalling 46 lots of various products because of a lack of sterility assurance.
Pharmedium Services, LLC
Stability Data Does Not Support Expiry: potential loss of potency in drugs packaged and stored in syringes.
Hospira Inc.
Lack of Assurance of Sterility: Loose crimp applied to the fliptop vial.
Premier Pharmacy Labs Inc
Lack of Assurance of Sterility: FDA inspection found insufficient environmental controls, potential cross contamination and lack of product specific process validations that can result in a lack of sterility assurance.
Side Effects Reported to FDA
FDA FAERS database · These are reported events, not confirmed side effects
Full Prescribing Information
Indications & Usage
1 INDICATIONS AND USAGE Succinylcholine chloride injection is indicated in adults and pediatric patients: as an adjunct to general anesthesia to facilitate tracheal intubation to provide skeletal muscle relaxation during surgery or mechanical ventilation. Succinylcholine chloride is a depolarizing neuromuscular blocker indicated in adults and pediatric patients: as an adjunct to general anesthesia ( 1 ) to facilitate tracheal intubation ( 1 ) to provide skeletal muscle relaxation during surgery or mechanical ventilation. ( 1 )
Dosage & Administration
2 DOSAGE AND ADMINISTRATION For intravenous or intramuscular use only. ( 2.1 ) Individualize dosage after careful assessment of the patient. ( 2.1 ) Accidental administration of neuromuscular blocking agents may be fatal. Store succinylcholine chloride injection with the cap and ferrule intact and in a manner that minimizes the possibility of selecting the wrong product. ( 2.1 ) See full prescribing information for succinylcholine chloride injection dosage recommendations, preparation instructions, and administration information. ( 2.2 , 2.3 , 2.4 , 2.5 , 2.6 ) 2.1 Important Dosage and Administration Information Succinylcholine chloride injection is for intravenous or intramuscular use only. Succinylcholine chloride injection must be titrated to effect by or under supervision of experienced clinicians who are familiar with its actions and with appropriate neuromuscular monitoring techniques. Succinylcholine chloride injection should be administered only by those skilled in the management of artificial respiration and only when facilities are instantly available for tracheal intubation and for providing adequate ventilation of the patient, including the administration of oxygen unde…
Contraindications
4 CONTRAINDICATIONS Succinylcholine chloride is contraindicated: in patients with skeletal muscle myopathies [see Warnings and Precautions ( 5.1 )] in patients with known hypersensitivity to succinylcholine. Severe anaphylactic reactions to succinylcholine have been reported [see Warnings and Precautions ( 5.2 )] after the acute phase of injury following major burns, multiple trauma, extensive denervation of skeletal muscle, or upper motor neuron injury, which may result in severe hyperkalemia and cardiac arrest [see Warnings and Precautions ( 5.4 )] in patients with known or suspected genetic susceptibility to malignant hyperthermia [see Warnings and Precautions ( 5.5 ), Clinical Pharmacology ( 12.5 )] Skeletal muscle myopathies ( 4 ) Known hypersensitivity to succinylcholine ( 4 ) After the acute phase of injury following major burns, multiple trauma, extensive denervation of skeletal muscle, or upper motor neuron injury ( 4 ) Known or suspected genetic susceptibility to malignant hyperthermia ( 4 )
Drug Interactions
7 DRUG INTERACTIONS Drugs that May Enhance the Neuromuscular Blocking Action of Succinylcholine : promazine, oxytocin, aprotinin, certain non-penicillin antibiotics, quinidine, β-adrenergic blockers, procainamide, lidocaine, trimethaphan, lithium carbonate, magnesium salts, quinine, chloroquine, isoflurane, desflurane, metoclopramide, terbutaline, and drugs that reduce plasma cholinesterase activity. ( 7.1 ) 7.1 Drugs that May Affect the Neuromuscular Blocking Action of Succinylcholine Chloride Drugs that may enhance the neuromuscular blocking action of succinylcholine include: promazine, oxytocin, aprotinin, certain non-penicillin antibiotics, quinidine, β-adrenergic blockers, procainamide, lidocaine, trimethaphan, lithium carbonate, magnesium salts, quinine, chloroquine, isoflurane, desflurane, metoclopramide, and terbutaline. The neuromuscular blocking effect of succinylcholine may be enhanced by drugs that reduce plasma cholinesterase activity (e.g., chronically administered oral contraceptives, glucocorticoids, or certain monoamine oxidase inhibitors) or by drugs that irreversibly inhibit plasma cholinesterase [see Warnings and Precautions ( 5.9 )]. If other neuromuscular bloc…
Adverse Reactions
6 ADVERSE REACTIONS The following clinically significant adverse reactions are discussed in greater detail in other sections of the labeling: Ventricular Dysrhythmias, Cardiac Arrest, and Death from Hyperkalemic Rhabdomyolysis in Pediatric Patients [see Warnings and Precautions ( 5.1 )] Anaphylaxis [see Warnings and Precautions ( 5.2 )] Hyperkalemia [see Warnings and Precautions ( 5.4 )] Malignant Hyperthermia [see Warnings and Precautions ( 5.5 )] Bradycardia [see Warnings and Precautions ( 5.6 )] Increase in Intraocular Pressure [see Warnings and Precautions ( 5.7 )] Prolonged Neuromuscular Block due to Phase II Block and Tachyphylaxis [see Warnings and Precautions ( 5.8 )]. The following adverse reactions associated with the use of succinylcholine were identified in clinical studies or postmarketing reports. Because some of these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure: Cardiovascular disorders: Cardiac arrest, arrhythmias, bradycardia, tachycardia, hypertension, hypotension Electrolyte disorders: Hyperkalemia Eye disorders: Increase…
Frequently Asked Questions
What is Succinylcholine Chloride used for?
Succinylcholine Chloride contains Succinylcholine Chloride. It is a injection taken intramuscular. Consult your doctor for specific uses.
Is Succinylcholine Chloride a controlled substance?
Succinylcholine Chloride is not classified as a controlled substance by the DEA.
What is the generic name for Succinylcholine Chloride?
The generic name for Succinylcholine Chloride is Succinylcholine Chloride. There are 3 other brand versions of Succinylcholine Chloride.
What is the NDC code for Succinylcholine Chloride 200 mg/10mL?
The NDC (National Drug Code) for Succinylcholine Chloride 200 mg/10mL is 42571-371, listed by Micro Labs Limited.
Other Succinylcholine Chloride Dosages
- Succinylcholine Chloride20 mg/mL14445-407
- Succinylcholine Chloride20 mg/mL31722-981
- Succinylcholine Chloride20 mg/mL70069-783
- Succinylcholine Chloride20 mg/mL70518-4409
- Succinylcholine Chloride20 mg/mL84549-301
- Succinylcholine Chloride20 mg/mL68083-450
- Succinylcholine Chloride20 mg/mL70069-301
- Succinylcholine Chloride20 mg/mL0143-9338
Other Succinylcholine Brands
See all →Not medical advice. Always consult your doctor or pharmacist before making any medication decisions.
Data from openFDA · Public domain (CC0 1.0)