Drugplain

RiVive 3 mg/.1mL

naloxone hydrochloride · SPRAY · Harm Reduction Therapeutics, Inc.

No Recall History
Plain English

Rivive is a nasal spray containing naloxone that is used to rapidly reverse opioid overdose in emergency situations. This medication is available over-the-counter and works by blocking the effects of opioids in the body.

Key Facts

Brand Name
RiVive
Generic Name
naloxone hydrochloride
NDC Code (Product)
82954-0100
Manufacturer
Harm Reduction Therapeutics, Inc.
Strength
3 mg/.1mL
Dosage Form
SPRAY
Route
NASAL
Marketing Status
Application #
NDA217722
Marketing Start
01/02/2024

Recall History

No Recall History

Side Effects Reported to FDA

FDA FAERS database · These are reported events, not confirmed side effects

drug ineffective93 reports
toxicity to various agents76 reports
vomiting59 reports
fatigue49 reports
off label use48 reports
drug withdrawal syndrome45 reports
nausea45 reports
overdose41 reports
diarrhoea40 reports
pain40 reports

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

Uses • to “revive” someone during an overdose from many prescription pain medications or street drugs such as heroin • this medicine can save a life

Dosage & Administration

Directions Step 1: CHECK if you suspect an overdose • CHECK for a suspected overdose : the person will not wake up or is very sleepy or not breathing well • Yell “Wake up!” • Shake the person gently • If the person is not awake, go to Step 2 Step 2: GIVE 1 st dose in the nose • Hold nasal spray device with thumb on plunger and a finger on each side of the nozzle • Insert nozzle into one nostril and press plunger firmly • Each nasal spray device contains only one dose of naloxone Step 3: CALL 911 • Get medical help immediately after giving the first dose • Call 911 now Step 4: WATCH & GIVE • WAIT 2-3 minutes after the 1 st dose to give the medicine time to work • If the person wakes up : Go to Step 5 • If the person does not wake up : • Give a second dose of medicine using a new nasal spray device • It is safe to keep giving doses every 2-3 minutes until the person wakes up Step 5: STAY • STAY until ambulance arrives: even if the person wakes up • GIVE another dose if the person becomes very sleepy again • You may need to give all the doses in the pack Step 1 Step 2 Step 3 Step 4 Step 5

Warnings

Warning When using this product some people may experience symptoms when they wake up, such as shaking, sweating, nausea, or feeling angry. This is to be expected.

Frequently Asked Questions

What is RiVive used for?

Rivive is a nasal spray containing naloxone that is used to rapidly reverse opioid overdose in emergency situations. This medication is available over-the-counter and works by blocking the effects of opioids in the body.

Is RiVive a controlled substance?

RiVive is not classified as a controlled substance by the DEA.

What is the generic name for RiVive?

The generic name for RiVive is naloxone hydrochloride. There are 12 other brand versions of naloxone hydrochloride.

What is the NDC code for RiVive 3 mg/.1mL?

The NDC (National Drug Code) for RiVive 3 mg/.1mL is 82954-0100, listed by Harm Reduction Therapeutics, Inc..

Product NDC

82954-0100

Package NDC

82954-0100-1

Other Naloxone Brands

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Not medical advice. Always consult your doctor or pharmacist before making any medication decisions.

Data from openFDA · Public domain (CC0 1.0)