Drugplain

Proparacaine Hydrochloride 5 mg/mL

Proparacaine Hydrochloride · SOLUTION/ DROPS · Sandoz Inc.

6 Recalls on Record
Plain English

Proparacaine Hydrochloride is a local anesthetic eye drop used to numb the surface of the eye for medical procedures and eye exams. It works by blocking pain signals in the eye to provide temporary relief during ophthalmologic procedures.

Key Facts

Brand Name
Proparacaine Hydrochloride
Generic Name
Proparacaine Hydrochloride
NDC Code (Product)
61314-016
Manufacturer
Sandoz Inc.
Strength
5 mg/mL
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Marketing Status
Application #
ANDA080027
Marketing Start
06/05/2000

Recall History

6 Recalls on Record
Class III12/26/2019

Akorn, Inc.

Chemical contamination; out of specification results obtained for equipment cleaning residue rinse sample

TerminatedVoluntary: Firm initiated
Class II10/13/2022

Akorn, Inc.

CGMP Deviations:

OngoingVoluntary: Firm initiated
Class II07/02/2019

Altaire Pharmaceuticals, Inc.

Lack of Assurance of Sterility

CompletedVoluntary: Firm initiated
Class II07/02/2019

Altaire Pharmaceuticals, Inc.

Lack of Assurance of Sterility

CompletedVoluntary: Firm initiated
Class II10/13/2022

Akorn, Inc.

CGMP Deviations:

OngoingVoluntary: Firm initiated
Class II09/11/2024

Mckesson Medical-Surgical Inc. Corporate Office

Temperature abuse: Products exposed to improper temperature above drug label specifications.

TerminatedVoluntary: Firm initiated

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

INDICATIONS AND USAGE Proparacaine hydrochloride ophthalmic solution is indicated for procedures in which a topical ophthalmic anesthetic is indicated: corneal anesthesia of short duration, e.g. tonometry, gonioscopy, removal of corneal foreign bodies, and for short corneal and conjunctival procedures.

Dosage & Administration

DOSAGE AND ADMINISTRATION Usual Dosage: Removal of foreign bodies and sutures, and for tonometry: 1 to 2 drops (in single instillations) in each eye before operating. Short corneal and conjunctival procedures: 1 drop in each eye every 5 to 10 minutes for 5 to 7 doses. NOTE: Proparacaine hydrochloride ophthalmic solution should be clear to straw-color. If the solution becomes darker, discard the solution.

Warnings

WARNINGS NOT FOR INJECTION - FOR TOPICAL OPHTHALMIC USE ONLY. Prolonged use of a topical ocular anesthetic is not recommended. It may produce permanent corneal opacification with accompanying visual loss.

Contraindications

CONTRAINDICATIONS Proparacaine hydrochloride ophthalmic solution should be considered contraindicated in patients with known hypersensitivity to any of the ingredients of this preparation.

Adverse Reactions

ADVERSE REACTIONS Occasional temporary stinging, burning and conjunctival redness may occur with the use of proparacaine. A rare, severe, immediate-type, apparently hyperallergic corneal reaction characterized by acute, intense and diffuse epithelial keratitis, a gray, ground glass appearance, sloughing of large areas of necrotic epithelium, corneal filaments and, sometimes, iritis with descemetitis has been reported. Allergic contact dermatitis from proparacaine with drying and fissuring of the fingertips has also been reported.

Frequently Asked Questions

What is Proparacaine Hydrochloride used for?

Proparacaine Hydrochloride is a local anesthetic eye drop used to numb the surface of the eye for medical procedures and eye exams. It works by blocking pain signals in the eye to provide temporary relief during ophthalmologic procedures.

Is Proparacaine Hydrochloride a controlled substance?

Proparacaine Hydrochloride is not classified as a controlled substance by the DEA.

What is the generic name for Proparacaine Hydrochloride?

The generic name for Proparacaine Hydrochloride is Proparacaine Hydrochloride. There are 4 other brand versions of Proparacaine Hydrochloride.

What is the NDC code for Proparacaine Hydrochloride 5 mg/mL?

The NDC (National Drug Code) for Proparacaine Hydrochloride 5 mg/mL is 61314-016, listed by Sandoz Inc..