Drugplain

POKONZA .75 g/.79g

Potassium Chloride · POWDER, FOR SOLUTION · Carwin Pharmaceutical Associates, LLC

No Recall HistoryCurrently in Shortage
Plain English

POKONZA is a powder, for solution containing potassium chloride at .75 g/.79g, taken oral. Manufactured by Carwin Pharmaceutical Associates, LLC.

Key Facts

Brand Name
POKONZA
Generic Name
Potassium Chloride
NDC Code (Product)
15370-305
Manufacturer
Carwin Pharmaceutical Associates, LLC
Strength
.75 g/.79g
Dosage Form
POWDER, FOR SOLUTION
Route
ORAL
Marketing Status
Application #
NDA208019
Marketing Start
09/19/2023

Recall History

No Recall History

Side Effects Reported to FDA

FDA FAERS database · These are reported events, not confirmed side effects

diarrhoea6,576 reports
dyspnoea6,487 reports
nausea6,326 reports
fatigue6,137 reports
death4,498 reports
pneumonia4,400 reports
asthenia4,077 reports
vomiting4,033 reports
headache3,972 reports
off label use3,939 reports

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

1 INDICATIONS AND USAGE POKONZA ® (Potasium Chloride for Oral Solution, USP) is indicated for the treatment and prophylaxis of hypokalemia with or without metabolic alkalosis, in patients for whom dietary management with potassium-rich foods or diuretic dose reduction is insufficient. POKONZA ® (Potassium Chloride for Oral Solution, USP) is a potassium salt indicated for the treatment and prophylaxis of hypokalemia with or without metabolic alkalosis, in patients for whom dietary management with potassiumrich foods or diuretic dose reduction is insufficient. ( 1 )

Dosage & Administration

2 DOSAGE AND ADMINISTRATION Dilute prior to administration. ( 2.1 , 5.1 ) Monitor serum potassium and adjust dosage accordingly ( 2.2 , 2.3 ) If serum potassium concentration is <2.5 mEq/L, use intravenous potassium instead of oral supplementation ( 2.1 ) Treatment of hypokalemia: Adults: Initial doses range from 40-100 mEq/day in 2-5 divided doses: limit doses to 40 mEq per dose. Total daily dose should not exceed 200 mEq ( 2.2 ) Pediatric patients aged birth to 16 years old: 2-4 mEq/kg/day in divided doses; not to exceed 1 mEq/kg as a single dose or 40 mEq whichever is lower; if deficits are severe or ongoing losses are great, consider intravenous therapy. Total daily dose should not exceed 100 mEq ( 2.3 ) Maintenance or Prophylaxis of hypokalemia: Adults: Typical dose is 20 mEq per day ( 2.2 ) Pediatric patients aged birth to 16 years old: typical dose is 1 mEq/kg/day. Do not exceed 3 mEq/kg/day ( 2.3 ) 2.1 Administration and Monitoring Monitoring Monitor serum potassium and adjust dosages accordingly. For treatment of hypokalemia, monitor potassium levels daily or more often depending on the severity of hypokalemia until they return to normal. Monitor potassium levels monthly t

Contraindications

4 CONTRAINDICATIONS POKONZA ® is contraindicated in patients on potassium sparing diuretics. Concomitant use with potassium sparing diuretics. ( 4 )

Drug Interactions

7 DRUG INTERACTIONS Potassium sparing diuretics: Avoid concomitant use ( 7.1 ) Renin-angiotensin-aldosterone inhibitors: Monitor for hyperkalemia ( 7.2 ) Nonsteroidal Anti-Inflammatory drugs: Monitor for hyperkalemia ( 7.3 ) 7.1 Potassium-Sparing Diuretics Use with potassium-sparing diuretics can produce severe hyperkalemia. Avoid concomitant use. 7.2 Renin-Angiotensin-Aldosterone System Inhibitors Drugs that inhibit the renin-angiotensin-aldosterone system (RAAS) including angiotensin converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), spironolactone, eplerenone, or aliskiren produce potassium retention by inhibiting aldosterone production. Closely monitor potassium in patients receiving concomitant RAAS therapy. 7.3 Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) NSAIDs may produce potassium retention by reducing renal synthesis of prostaglandin E and impairing the renin-angiotensin system. Closely monitor potassium in patients on concomitant NSAIDs.

Adverse Reactions

6 ADVERSE REACTIONS The most common adverse reactions to oral potassium salts are nausea, vomiting, flatulence, abdominal pain/discomfort, and diarrhea. Most common adverse reactions are nausea, vomiting, flatulence, abdominal pain/discomfort, and diarrhea. ( 6 ) To report SUSPECTED ADVERSE REACTIONS, contact Carwin Pharmaceutical Associates at 1-844-700-5011 or FDA at 1-800-FDA-1088 or www.fda.gov/ medwatch.

Frequently Asked Questions

What is POKONZA used for?

POKONZA contains Potassium Chloride. It is a powder, for solution taken oral. Consult your doctor for specific uses.

Is POKONZA a controlled substance?

POKONZA is not classified as a controlled substance by the DEA.

What is the generic name for POKONZA?

The generic name for POKONZA is Potassium Chloride. There are 11 other brand versions of Potassium Chloride.

What is the NDC code for POKONZA .75 g/.79g?

The NDC (National Drug Code) for POKONZA .75 g/.79g is 15370-305, listed by Carwin Pharmaceutical Associates, LLC.