PHYSOSTIGMINE SALICYLATE 1 mg/mL
PHYSOSTIGMINE SALICYLATE · INJECTION · HF Acquisition Co LLC, DBA HealthFirst
Physostigmine salicylate is a prescription injection given intravenously that works by increasing levels of the neurotransmitter acetylcholine in the brain and body. It is used to treat certain types of poisoning, including overdoses from anticholinergic drugs and atropine.
Key Facts
- Brand Name
- PHYSOSTIGMINE SALICYLATE
- Generic Name
- PHYSOSTIGMINE SALICYLATE
- NDC Code (Product)
51662-1439- Manufacturer
- HF Acquisition Co LLC, DBA HealthFirst
- Strength
- 1 mg/mL
- Dosage Form
- INJECTION
- Route
- INTRAVENOUS
- Marketing Status
- Marketing Start
- 12/22/2019
Recall History
No Recall HistoryFull Prescribing Information
Indications & Usage
INDICATIONS & USAGE To reverse the effect upon the central nervous system, caused by clinical or toxic dosages of drugs capable of producing the anticholinergic syndrome.
Dosage & Administration
DOSAGE & ADMINISTRATION Past Anesthesia Care: 0.5 to 1.0 mg intramuscularly or intravenously. INTRAVENOUS ADMINISTRATION SHOULD BE AT A SLOW CONTROLLED RATE OF NO MORE THAN 1 MG PER MINUTE. Dosage may be repeated at intervals of 10 to 30 minutes if desired patient response is not obtained.
Warnings
WARNINGS Contains sodium bisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in non-asthmatic people. If excessive symptoms of salivation, emesis, urination and defecation occur, the use of Physostigmine Salicylate Injection should be terminated. If excessive sweating or nausea occur, the dosage should be reduced. Intravenous administration should be at a slow, controlled rate, no more than 1 mg per minute (see DOSAGE . Rapid administration can cause bradycardia, hypersalivation leading to a respiratory difficulties and possible convulsions. An overdosage of Physostigmine Salicylate Injection can cause a cholinergic crisis.
Contraindications
CONTRAINDICATIONS Physostigmine Salicylate Injection should not be used in the presence of asthma, gangrene, diabetes, cardiovascular disease, mechanical obstruction of the intestine or urogenital tract or any vagotonic state, and in patients receiving choline esters and depolarizing neuromuscular blocking agents (decamethonium, succinylcholine). For post-anesthesia, the concomitant use of atropine with physostigmine salicylate is not recommended, since the atropine antagonizes the action of physostigmine.
Adverse Reactions
ADVERSE REACTIONS Nausea, vomiting and salivation; can be offset by reducing dosage. Bradycardia and convulsions, if intravenous administration is too rapid. See DOSAGE AND ADMINISTRATION.
Frequently Asked Questions
What is PHYSOSTIGMINE SALICYLATE used for?
Physostigmine salicylate is a prescription injection given intravenously that works by increasing levels of the neurotransmitter acetylcholine in the brain and body. It is used to treat certain types of poisoning, including overdoses from anticholinergic drugs and atropine.
Is PHYSOSTIGMINE SALICYLATE a controlled substance?
PHYSOSTIGMINE SALICYLATE is not classified as a controlled substance by the DEA.
What is the generic name for PHYSOSTIGMINE SALICYLATE?
The generic name for PHYSOSTIGMINE SALICYLATE is PHYSOSTIGMINE SALICYLATE. There are 1 other brand versions of PHYSOSTIGMINE SALICYLATE.
What is the NDC code for PHYSOSTIGMINE SALICYLATE 1 mg/mL?
The NDC (National Drug Code) for PHYSOSTIGMINE SALICYLATE 1 mg/mL is 51662-1439, listed by HF Acquisition Co LLC, DBA HealthFirst.