Drugplain

Phenobarbital Oral Solution 20 mg/5mL

Phenobarbital Oral · SOLUTION · Kesin Pharma Corporation

2 Recalls on RecordCurrently in Shortage
Plain English

Phenobarbital Oral Solution is a solution containing phenobarbital oral at 20 mg/5mL, taken oral. Manufactured by Kesin Pharma Corporation.

Key Facts

Brand Name
Phenobarbital Oral Solution
Generic Name
Phenobarbital Oral
NDC Code (Product)
81033-164
Manufacturer
Kesin Pharma Corporation
Strength
20 mg/5mL
Dosage Form
SOLUTION
Route
ORAL
Marketing Status
DEA Schedule
Schedule IV (Controlled)
Marketing Start
11/05/2025

Recall History

2 Recalls on Record
Class II03/25/2019

Lohxa LLC

Labeling: Incorrect or Missing Lot and/or Exp Date - the label contains an incorrect Exp Date.

TerminatedVoluntary: Firm initiated
Class II05/21/2019

Torrent Pharma Inc

cGMP Deviations: Potential product contamination with Burkholderia cepacia (B.cepacia) and Ralstonia pickettii (R. pickettii).

TerminatedVoluntary: Firm initiated

Side Effects Reported to FDA

FDA FAERS database · These are reported events, not confirmed side effects

anticonvulsant drug level increased1 reports
asthenia1 reports
bronchiolitis1 reports
cough1 reports
drooling1 reports
drug interaction1 reports
hepatic enzyme increased1 reports
lethargy1 reports
mental status changes1 reports
pneumonia1 reports

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

INDICATIONS USAGE A. Sedative B. Anticonvulsant - For the treatment of generalized and partial seizures.

Dosage & Administration

DOSAGE & ADMINISTRATION The dose of phenobarbital must be individualized with full knowledge of its particular characteristics. Factors of consideration are the patient’s age, weight, and condition. Sedation For sedation, the drug may be administered in single doses of 30 to 120 mg repeated at intervals; frequency will be determined by the patient’s response. It is generally considered that no more than 400 mg of phenobarbital should be administered during a 24-hour period. Adults: Daytime Sedation: 30 to 120 mg daily in 2 to 3 divided doses. Oral Hypnotic: 100 to 200 mg. Anticonvulsant Use Clinical laboratories reference values should be used to determine the therapeutic anticonvulsant level of phenobarbital in the serum. To achieve the blood levels considered therapeutic in pediatric patients, higher per-kilogram dosages are generally necessary for phenobarbital and most other anticonvulsants. In pediatric patients and infants, phenobarbital at a loading dose of 15 to 20 mg/kg produces blood levels of about 20 mcg/mL shortly after administration. Phenobarbital has been used in the treatment and prophylaxis of febrile seizures. However, it has not been established that prevention

Warnings

WARNINGS 1. Habit Forming Phenobarbital may be habit forming. Tolerance and psychological and physical dependence may occur with continued use (see DRUG ABUSE AND DEPENDENCE and Pharmacokinetics under CLINICAL PHARMACOLOGY ). Patients who have psychologic dependence on barbiturates may increase the dosage or decrease the dosage interval without consulting a physician and may subsequently develop a physical dependence on barbiturates. In order to minimize the possibility of overdosage or the development of dependence, the prescribing and dispensing of sedative-hypnotic barbiturates should be limited to the amount required for the interval until the next appointment. Abrupt cessation after prolonged use in a person who is dependent on the drug may result in withdrawal symptoms, including delirium, convulsions, and possibly death. Barbiturates should be withdrawn gradually from any patient known to be taking excessive doses over long periods of time (see DRUG ABUSE AND DEPENDENCE ). 2. Acute or Chronic Pain Caution should be exercised when barbiturates are administered to patients with acute or chronic pain, because paradoxical excitement could be induced or important symptoms could b

Contraindications

CONTRAINDICATIONS Phenobarbital is contraindicated in patients who are hypersensitive to barbiturates, in patients with a history of manifest or latent porphyria, and in patients with marked impairment of liver function or respiratory disease in which dyspnea or obstruction is evident.

Adverse Reactions

ADVERSE REACTIONS The following adverse reactions have been reported: CNS Depression - Residual sedation or “hangover”, drowsiness, lethargy, and vertigo. Emotional disturbances and phobias may be accentuated. In some persons, barbiturates such as phenobarbital repeatedly produce excitement rather than depression, and the patient may appear to be inebriated. Irritability and hyperactivity can occur in children. Like other nonanalgesic hypnotic drugs, barbiturates such as phenobarbital, when given in the presence of pain, may cause restlessness, excitement, and even delirium. Rarely, the use of barbiturates results in the localized or diffuse myalgic, neuralgic, or arthritic pain, especially in psychoneurotic patients with insomnia. The pain may appear in paroxysms, is most intense in the early morning hours, and is most frequently located in the region of the neck, shoulder girdle, and upper limbs. Symptoms may last for days after the drug is discontinued. Respiratory/Circulatory - Respiratory depression, apnea, circulatory collapse. Allergic - Acquired hypersensitivity to barbiturates consists chiefly in allergic reactions that occur especially in persons who tend to have asthma,

Frequently Asked Questions

What is Phenobarbital Oral Solution used for?

Phenobarbital Oral Solution contains Phenobarbital Oral. It is a solution taken oral. Consult your doctor for specific uses.

Is Phenobarbital Oral Solution a controlled substance?

Yes, Phenobarbital Oral Solution is classified as CIV under the DEA Controlled Substances Act.

What is the generic name for Phenobarbital Oral Solution?

The generic name for Phenobarbital Oral Solution is Phenobarbital Oral. There are no other listed brand versions of Phenobarbital Oral.

What is the NDC code for Phenobarbital Oral Solution 20 mg/5mL?

The NDC (National Drug Code) for Phenobarbital Oral Solution 20 mg/5mL is 81033-164, listed by Kesin Pharma Corporation.

Product NDC

81033-164

Package NDC

81033-164-47

Not medical advice. Always consult your doctor or pharmacist before making any medication decisions.

Data from openFDA · Public domain (CC0 1.0)