Drugplain

Nystatin Oral Suspension 100000 [USP'U]/mL

NYSTATIN · SUSPENSION · Xttrium Laboratories, Inc.

10 Recalls on Record
Plain English

Nystatin oral suspension is a prescription antifungal medication used to treat fungal infections in the mouth and throat. It works by stopping the growth of fungus and is taken by mouth as a liquid.

Key Facts

Brand Name
Nystatin Oral Suspension
Generic Name
NYSTATIN
NDC Code (Product)
0116-4026
Manufacturer
Xttrium Laboratories, Inc.
Strength
100000 [USP'U]/mL
Dosage Form
SUSPENSION
Route
ORAL
Marketing Status
Application #
ANDA062512
Drug Class
Polyene Antifungal [EPC]
Marketing Start
02/06/2026

Recall History

10 Recalls on Record
Class II01/14/2020

Pharmaceutical Associates Inc

Subpotent: Out of specification for assay at the 12-month time point.

TerminatedVoluntary: Firm initiated
Class II08/04/2020

PAI Holdings, LLC. dba Pharmaceutical Associates Inc

Subpotent drug: Out of specification for assay at the 15-month test interval.

TerminatedVoluntary: Firm initiated
Class III05/17/2017

VistaPharm, Inc.

Failed Impurities/Degradation Specifications: Presence of an impurity peak that exceeds approved specification.

TerminatedVoluntary: Firm initiated
Class III05/29/2018

Pharmaceutical Associates Inc

Resuspension problems: Out of specification for appearance and resuspendability.

TerminatedVoluntary: Firm initiated
Class III06/23/2020

VistaPharm, Inc.

Failed impurities/degradation products; Presence of an impurity peak that exceeds the approved specification.

TerminatedVoluntary: Firm initiated
Class II01/18/2017

VistaPharm, Inc.

CGMP Deviations: Purified water used to manufacture the drug products may have been contaminated with Burkholderia cepacia.

TerminatedVoluntary: Firm initiated
Class III03/28/2019

Akorn, Inc.

Failed Impurities/Degradation Specifications: Out of Specification for an unknown impurity was observed during the 18 month stability testing.

TerminatedVoluntary: Firm initiated
Class III09/25/2020

VistaPharm, Inc.

Failed Impurties/Degradation Specifications: out of specification results for an impurity for one lot

TerminatedVoluntary: Firm initiated
Class II03/19/2020

PAI Holdings, LLC. dba Pharmaceutical Associates Inc

SubPotent Drug: Low out-of-specification results for assay testing.

TerminatedVoluntary: Firm initiated
Class III06/23/2020

VistaPharm, Inc.

Failed impurities/degradation products; Presence of an impurity peak that exceeds the approved specification.

TerminatedVoluntary: Firm initiated

Side Effects Reported to FDA

FDA FAERS database · These are reported events, not confirmed side effects

nausea1,942 reports
diarrhoea1,738 reports
fatigue1,736 reports
pneumonia1,600 reports
dyspnoea1,451 reports
off label use1,393 reports
vomiting1,340 reports
pain1,202 reports
drug ineffective1,200 reports
death1,120 reports

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

INDICATIONS AND USAGE Nystatin Oral Suspension is indicated for the treatment of candidiasis in the oral cavity.

Dosage & Administration

DOSAGE AND ADMINISTRATION INFANTS: 2 mL (200,000 units) four times daily (in infants and young children, use dropper to place one-half of dose in each side of mouth and avoid feeding for 5 to 10 minutes). NOTE: Limited clinical studies in premature and low birth weight infants indicate that 1 mL four times daily is effective. CHILDREN AND ADULTS: 4-6 mL (400,000 to 600,000 units) four times daily (one-half of dose in each side of mouth). The preparation should be retained in the mouth as long as possible before swallowing. Continue treatment for at least 48 hours after perioral symptoms have disappeared and cultures demonstrate eradication of Candida albicans .

Contraindications

CONTRAINDICATIONS The preparation is contraindicated in patients with a history of hypersensitivity to any of its components.

Adverse Reactions

ADVERSE REACTIONS Nystatin is well tolerated even with prolonged therapy. Oral irritation and sensitization have been reported. (See PRECAUTIONS: General ). Gastrointestinal: Diarrhea (including one case of bloody diarrhea), nausea, vomiting, gastrointestinal upset/disturbances. Dermatologic: Rash, including urticaria has been reported rarely. Stevens-Johnson syndrome has been reported very rarely. Other: Tachycardia, bronchospasm, facial swelling, and non-specific myalgia have also been rarely reported. To report SUSPECTED ADVERSE REACTIONS, contact Xttrium Laboratories, Inc. at 1-800-587-3721 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Frequently Asked Questions

What is Nystatin Oral Suspension used for?

Nystatin oral suspension is a prescription antifungal medication used to treat fungal infections in the mouth and throat. It works by stopping the growth of fungus and is taken by mouth as a liquid.

Is Nystatin Oral Suspension a controlled substance?

Nystatin Oral Suspension is not classified as a controlled substance by the DEA.

What is the generic name for Nystatin Oral Suspension?

The generic name for Nystatin Oral Suspension is NYSTATIN. There are 11 other brand versions of NYSTATIN.

What is the NDC code for Nystatin Oral Suspension 100000 [USP'U]/mL?

The NDC (National Drug Code) for Nystatin Oral Suspension 100000 [USP'U]/mL is 0116-4026, listed by Xttrium Laboratories, Inc..