Nighttime SEVERE 325 mg/15mL
acetaminophen, dextromethorphan hydrobromide, doxylamine succinate, phenylephrine hydrochloride · SOLUTION · H E B
Nighttime Severe is an over-the-counter liquid medication that combines acetaminophen (a pain reliever and fever reducer), dextromethorphan (a cough suppressant), doxylamine (a sleep aid), and phenylephrine (a nasal decongestant) to help relieve multiple cold and flu symptoms at night. This combination product is intended to reduce pain, fever, cough, and congestion while helping you sleep.
Key Facts
- Brand Name
- Nighttime SEVERE
- Generic Name
- acetaminophen, dextromethorphan hydrobromide, doxylamine succinate, phenylephrine hydrochloride
- NDC Code (Product)
59640-423- Manufacturer
- H E B
- Strength
- 325 mg/15mL
- Dosage Form
- SOLUTION
- Route
- ORAL
- Marketing Status
- Application #
- M012
- Marketing Start
- 08/08/2025
Recall History
No Recall HistoryFrequently Asked Questions
What is Nighttime SEVERE used for?
Nighttime Severe is an over-the-counter liquid medication that combines acetaminophen (a pain reliever and fever reducer), dextromethorphan (a cough suppressant), doxylamine (a sleep aid), and phenylephrine (a nasal decongestant) to help relieve multiple cold and flu symptoms at night. This combination product is intended to reduce pain, fever, cough, and congestion while helping you sleep.
Is Nighttime SEVERE a controlled substance?
Nighttime SEVERE is not classified as a controlled substance by the DEA.
What is the generic name for Nighttime SEVERE?
The generic name for Nighttime SEVERE is acetaminophen, dextromethorphan hydrobromide, doxylamine succinate, phenylephrine hydrochloride. There are 12 other brand versions of acetaminophen, dextromethorphan hydrobromide, doxylamine succinate, phenylephrine hydrochloride.
What is the NDC code for Nighttime SEVERE 325 mg/15mL?
The NDC (National Drug Code) for Nighttime SEVERE 325 mg/15mL is 59640-423, listed by H E B.
Other Acetaminophen, Brands
See all →- basic care nighttime severe cold and flu650 mg/30mL72288-189
- basic care nighttime severe cold and flu325 mg/172288-721
- NiteTime SEVERE Cold and Flu Relief SOFTGELS325 mg/176162-637
- Equate Health Non Drowsy DAY Cold and Flu Plus and NIGHTTIME Cold and Flu Plus79903-133
- Goodnow Cold and Flu Day Relief Cold and Flu Night Relief82501-0733
- nitetime severe650 mg/30mL56062-763
- Alka-Seltzer Plus Maximum Strength Night Cold and Flu PowerMax Gels325 mg/10280-1640
- Night Time Cold and Flu325 mg/172476-998
- Daytime Nighttime Cold and Flu79903-383
- good sense night time cold and flu325 mg/15mL0113-2501
Not medical advice. Always consult your doctor or pharmacist before making any medication decisions.
Data from openFDA · Public domain (CC0 1.0)