Drugplain

Montelukast Sodium 5 mg/1

Montelukast · TABLET, CHEWABLE · Amneal Pharmaceuticals LLC

10 Recalls on RecordCurrently in Shortage
Plain English

Montelukast Sodium is a tablet, chewable containing montelukast at 5 mg/1, taken oral. Manufactured by Amneal Pharmaceuticals LLC.

Key Facts

Brand Name
Montelukast Sodium
Generic Name
Montelukast
NDC Code (Product)
65162-772
Manufacturer
Amneal Pharmaceuticals LLC
Strength
5 mg/1
Dosage Form
TABLET, CHEWABLE
Route
ORAL
Marketing Status
Application #
ANDA205107
Marketing Start
09/04/2020

Recall History

10 Recalls on Record
Class III03/27/2023

Teva Pharmaceuticals USA Inc

Failed Impurities/Degradation Specifications: failed impurities for Sulphoxide and Impurity A.

TerminatedVoluntary: Firm initiated
Class II02/07/2023

Accord Healthcare, Inc.

CGMP Deviations: recalling drug products following an FDA inspection.

TerminatedVoluntary: Firm initiated
Class II11/14/2014

Attix Pharmaceuticals

Penicillin Cross Contamination: All lots of all products repackaged and distributed between 01/05/12 and 02/12/15 are being recalled because they were repackaged in a facility with penicillin products without adequate separation which could introduce the potential for cross contamination with penicillin.

TerminatedVoluntary: Firm initiated
Class II03/23/2023

Preferred Pharmaceuticals, Inc.

cGMP Deviations for the manufacturing Firm (Accord Healthcare) after their inspection.

OngoingVoluntary: Firm initiated
Class II04/06/2023

PD-Rx Pharmaceuticals, Inc.

CGMP deviations.

TerminatedVoluntary: Firm initiated
Class II08/20/2018

Hetero Labs Limited Unit V

Discoloration: A complaint was received from a pharmacist for the presence of blue specks on tablets.

TerminatedVoluntary: Firm initiated
Class III01/20/2020

Macleods Pharma Usa Inc

Failed Dissolution Specifications: testing revealed low out of specification result in one lot of product

TerminatedVoluntary: Firm initiated
Class II10/13/2023

Dr. Reddy's Laboratories, Inc.

Presence of Foreign Tablet(s)/Capsule(s): A foreign tablet was found in a bottle of Montelukast Sodium Tablets, USP 10mg, identified as metoprolol 25 mg.

TerminatedVoluntary: Firm initiated
Class II03/13/2023

Direct Rx

cGMP deviations

TerminatedVoluntary: Firm initiated
Class I08/15/2018

Hetero Labs Limited Unit V

Labeling: Label Mix-Up - One lot labeled Montelukast Sodium Tablets 10 mg tablets may contain 90 tablets of Losartan Potassium 50 mg.

OngoingVoluntary: Firm initiated

Side Effects Reported to FDA

FDA FAERS database · These are reported events, not confirmed side effects

dyspnoea7,947 reports
asthma7,658 reports
drug ineffective6,118 reports
fatigue5,665 reports
headache4,934 reports
cough4,789 reports
nausea4,334 reports
off label use4,049 reports
pneumonia4,005 reports
pain3,744 reports

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

1 INDICATIONS AND USAGE Montelukast sodium chewable tablets are a leukotriene receptor antagonist indicated for: • Prophylaxis and chronic treatment of asthma in patients 2 years of age and older ( 1.1 ). • Acute prevention of exercise-induced bronchoconstriction (EIB) in patients 6 years of age and older ( 1.2 ). • Relief of symptoms of allergic rhinitis (AR): seasonal allergic rhinitis (SAR) in patients 2 years of age and older, and perennial allergic rhinitis (PAR) in patients 2 years of age and older. Reserve use for patients who have an inadequate response or intolerance to alternative therapies ( 1.3 ). 1.1 Asthma Montelukast sodium chewable tablets are indicated for the prophylaxis and chronic treatment of asthma in adults and pediatric patients 2 years of age and older. 1.2 Exercise-Induced Bronchoconstriction (EIB) Montelukast sodium chewable tablets are indicated for prevention of exercise-induced bronchoconstriction (EIB) in patients 6 years of age and older. 1.3 Allergic Rhinitis sodium chewable tablets are indicated for the relief of symptoms of seasonal allergic rhinitis in patients 2 years of age and older and perennial allergic rhinitis in patients 2 of age and olde

Dosage & Administration

2 DOSAGE AND ADMINISTRATION Administration (by indications): • Asthma ( 2.1 ): Once daily in the evening for patients 2 years and older. • Acute prevention of EIB ( 2.2 ): One tablet at least 2 hours before exercise for patients 6 years of age and older. • Seasonal allergic rhinitis ( 2.3 ): Once daily for patients 2 years and older. • Perennial allergic rhinitis ( 2.3 ): Once daily for patients 2 years and older. Dosage (by age) ( 2 ): • 15 years and older: one 10-mg tablet. • 6 to 14 years: one 5-mg chewable tablet. • 2 to 5 years: one 4-mg chewable tablet. Patients with both asthma and allergic rhinitis should take only one dose daily in the evening ( 2.4 ). 2.1 Asthma Montelukast sodium should be taken once daily in the evening. The following doses are recommended: For adults and adolescents 15 years of age and older: one 10-mg tablet. For pediatric patients 6 to 14 years of age: one 5-mg chewable tablet. For pediatric patients 2 to 5 years of age: one 4-mg chewable tablet. Safety and effectiveness in pediatric patients less than 12 months of age with asthma have not been established. who miss a dose should take the next dose at their regular time and should not take 2 doses at

Contraindications

4 CONTRAINDICATIONS • Hypersensitivity to any component of this product. • Hypersensitivity to any component of this product ( 4 ).

Drug Interactions

7 DRUG INTERACTIONS No dose adjustment is needed when montelukast sodium is co-administered with theophylline, prednisone, prednisolone, oral contraceptives, terfenadine, digoxin, warfarin, gemfibrozil, itraconazole, thyroid hormones, sedative hypnotics, non-steroidal anti-inflammatory agents, benzodiazepines, decongestants, and Cytochrome P450 (CYP) enzyme inducers [see Clinical Pharmacology ( 12.3 )] .

Adverse Reactions

6 ADVERSE REACTIONS Most common adverse reactions (incidence ≥5% and greater than placebo listed in descending order of frequency): upper respiratory infection, fever, headache, pharyngitis, cough, abdominal pain, diarrhea, otitis media, influenza, rhinorrhea, sinusitis, otitis ( 6.1 ). To report SUSPECTED ADVERSE REACTIONS, contact Hetero Labs Limited at 1-866-495-1995 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch . See 17 for PATIENT COUNSELING INFORMATION and Medication Guide. Revised: 05/2020 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice. In the following description of clinical trials experience, adverse reactions are listed regardless of causality assessment. The most common adverse reactions (incidence ≥5% and greater than placebo; listed in descending order of frequency) in controlled clinical trials were: upper respiratory infection, fever, headache, pharyngitis, cough, abdominal pain, diarrhea, otitis media, influenz

Frequently Asked Questions

What is Montelukast Sodium used for?

Montelukast Sodium contains Montelukast. It is a tablet, chewable taken oral. Consult your doctor for specific uses.

Is Montelukast Sodium a controlled substance?

Montelukast Sodium is not classified as a controlled substance by the DEA.

What is the generic name for Montelukast Sodium?

The generic name for Montelukast Sodium is Montelukast. There are 8 other brand versions of Montelukast.

What is the NDC code for Montelukast Sodium 5 mg/1?

The NDC (National Drug Code) for Montelukast Sodium 5 mg/1 is 65162-772, listed by Amneal Pharmaceuticals LLC.