Drugplain

Methenamine Hippurate 1 g/1

Methenamine Hippurate · TABLET · Jubilant Cadista Pharmaceuticals Inc.

No Recall History
Plain English

Methenamine hippurate is an oral tablet used to treat and prevent urinary tract infections by working as an antimicrobial agent in the urinary system. It is taken by mouth and comes in 1 gram tablet strength.

Key Facts

Brand Name
Methenamine Hippurate
Generic Name
Methenamine Hippurate
NDC Code (Product)
59746-797
Manufacturer
Jubilant Cadista Pharmaceuticals Inc.
Strength
1 g/1
Dosage Form
TABLET
Route
ORAL
Marketing Status
Application #
ANDA217675
Marketing Start
01/24/2023

Recall History

No Recall History

Side Effects Reported to FDA

FDA FAERS database · These are reported events, not confirmed side effects

urinary tract infection150 reports
diarrhoea75 reports
nausea75 reports
drug ineffective73 reports
fall71 reports
fatigue71 reports
headache60 reports
dizziness55 reports
product dose omission issue51 reports
death49 reports

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

INDICATIONS Methenamine hippurate tablets are indicated for prophylactic or suppressive treatment of frequently recurring urinary tract infections when long-term therapy is considered necessary. This drug should only be used after eradication of the infection by other appropriate antimicrobial agents. To reduce the development of drug-resistant bacteria and maintain the effectiveness of methenamine hippurate tablets and other antibacterial drugs, methenamine hippurate tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by susceptible bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.

Dosage & Administration

DOSAGE AND ADMINISTRATION 1 tablet (1.0 g) twice daily (morning and night) for adults and pediatric patients over 12 years of age. 1/2 to 1 tablet (0.5 to 1.0 g) twice daily (morning and night) for pediatric patients 6 to 12 years of age. Since the antibacterial activity of methenamine hippurate tablets is greater in acid urine, restriction of alkalinizing foods and medications is desirable. If necessary, as indicated by urinary pH and clinical response, supplemental acidification of the urine should be instituted. The efficacy of therapy should be monitored by repeated urine cultures.

Warnings

WARNING Large doses of methenamine (8 grams daily for 3 to 4 weeks) have caused bladder irritation, painful and frequent micturition, albuminuria, and gross hematuria.

Contraindications

CONTRAINDICATIONS Methenamine hippurate tablets are contraindicated in patients with renal insufficiency, severe hepatic insufficiency, or severe dehydration. Methenamine preparations should not be given to patients taking sulfonamides because some sulfonamides may form an insoluble precipitate with formaldehyde in the urine.

Adverse Reactions

ADVERSE REACTIONS Minor adverse reactions have been reported in less than 3.5% of patients treated. These reactions have included nausea, upset stomach, dysuria, and rash. To report SUSPECTED ADVERSE REACTIONS, contact Esjay Pharma LLC at 1-800-239-9339 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Frequently Asked Questions

What is Methenamine Hippurate used for?

Methenamine hippurate is an oral tablet used to treat and prevent urinary tract infections by working as an antimicrobial agent in the urinary system. It is taken by mouth and comes in 1 gram tablet strength.

Is Methenamine Hippurate a controlled substance?

Methenamine Hippurate is not classified as a controlled substance by the DEA.

What is the generic name for Methenamine Hippurate?

The generic name for Methenamine Hippurate is Methenamine Hippurate. There are 4 other brand versions of Methenamine Hippurate.

What is the NDC code for Methenamine Hippurate 1 g/1?

The NDC (National Drug Code) for Methenamine Hippurate 1 g/1 is 59746-797, listed by Jubilant Cadista Pharmaceuticals Inc..