Drugplain

ILEVRO 3 mg/mL

nepafenac · SUSPENSION/ DROPS · Novartis Pharmaceuticals Corporation

1 Recall on Record
Plain English

ILEVRO is a suspension/ drops containing nepafenac at 3 mg/mL, taken ophthalmic. Manufactured by Novartis Pharmaceuticals Corporation.

Key Facts

Brand Name
ILEVRO
Generic Name
nepafenac
NDC Code (Product)
0078-0743
Manufacturer
Novartis Pharmaceuticals Corporation
Strength
3 mg/mL
Dosage Form
SUSPENSION/ DROPS
Route
OPHTHALMIC
Marketing Status
Application #
NDA203491
Drug Class
Nonsteroidal Anti-inflammatory Drug [EPC]
Marketing Start
12/20/2012

Recall History

1 Recall on Record
Class II03/15/2021

Cardinal Health Inc.

CGMP Deviations: Intermittent exposure to temperature excursion during storage.

TerminatedVoluntary: Firm initiated

Side Effects Reported to FDA

FDA FAERS database · These are reported events, not confirmed side effects

eye pain376 reports
drug ineffective116 reports
vision blurred110 reports
eye irritation64 reports
off label use64 reports
product quality issue58 reports
visual impairment54 reports
liquid product physical issue53 reports
cataract52 reports
fatigue45 reports

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

1 INDICATIONS AND USAGE ILEVRO ® 0.3% is indicated for the treatment of pain and inflammation associated with cataract surgery. ILEVRO ® 0.3% is a nonsteroidal, anti-inflammatory prodrug indicated for the treatment of pain and inflammation associated with cataract surgery ( 1 ).

Dosage & Administration

2 DOSAGE AND ADMINISTRATION One drop of ILEVRO ® 0.3% should be applied to the affected eye one-time-daily beginning 1 day prior to cataract surgery, continued on the day of surgery and through the first 2 weeks of the postoperative period. An additional drop should be administered 30 to 120 minutes prior to surgery. ( 2 ) 2.1 Recommended Dosing One drop of ILEVRO ® 0.3% should be applied to the affected eye one time daily beginning 1 day prior to cataract surgery, continued on the day of surgery and through the first 2 weeks of the postoperative period. An additional drop should be administered 30 to 120 minutes prior to surgery. 2.2 Use with Other Topical Ophthalmic Medications ILEVRO ® 0.3% may be administered in conjunction with other topical ophthalmic medications such as beta-blockers, carbonic anhydrase inhibitors, alpha-agonists, cycloplegics, and mydriatics. If more than one topical ophthalmic medication is being used, the medicines must be administered at least 5 minutes apart.

Contraindications

4 CONTRAINDICATIONS ILEVRO ® 0.3% is contraindicated in patients with previously demonstrated hypersensitivity to any of the ingredients in the formula or to other nonsteroidal anti-inflammatory drugs (NSAIDs). Hypersensitivity to any of the ingredients in the formula or to other non-steroidal anti-inflammatory drugs (NSAIDS). ( 4 )

Adverse Reactions

6 ADVERSE REACTIONS Because clinical studies are conducted under widely varying conditions, adverse reaction rates observed in the clinical studies of a drug cannot be directly compared to the rates in the clinical studies of another drug and may not reflect the rates observed in practice. Most common adverse reactions (5% to 10%) are capsular opacity, decreased visual acuity, foreign body sensation, increased intraocular pressure, and sticky sensation. ( 6.1 ) To report SUSPECTED ADVERSE REACTIONS, contact Harrow Eye, LLC at 1-833-4HARROW or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch . 6.1 Serious and Otherwise Important Adverse Reactions The following adverse reactions are discussed in greater detail in other sections of labeling. Increased Bleeding Time [see Warnings and Precautions (5.1) ] Delayed Healing [see Warnings and Precautions (5.2) ] Corneal Effects [see Warnings and Precautions (5.3) ] 6.2 Ocular Adverse Reactions The most frequently reported ocular adverse reactions following cataract surgery were capsular opacity, decreased visual acuity, foreign body sensation, increased intraocular pressure (IOP), and sticky sensation. These reactions occurred in approximately

Frequently Asked Questions

What is ILEVRO used for?

ILEVRO contains nepafenac. It is a suspension/ drops taken ophthalmic. Consult your doctor for specific uses.

Is ILEVRO a controlled substance?

ILEVRO is not classified as a controlled substance by the DEA.

What is the generic name for ILEVRO?

The generic name for ILEVRO is nepafenac. There are 1 other brand versions of nepafenac.

What is the NDC code for ILEVRO 3 mg/mL?

The NDC (National Drug Code) for ILEVRO 3 mg/mL is 0078-0743, listed by Novartis Pharmaceuticals Corporation.

Product NDC

0078-0743

Other ILEVRO Dosages

Not medical advice. Always consult your doctor or pharmacist before making any medication decisions.

Data from openFDA · Public domain (CC0 1.0)