Drugplain

FILSUVEZ 100 mg/g

birch triterpenes · GEL · Chiesi USA, Inc.

No Recall History
Plain English

FILSUVEZ is a gel containing birch triterpenes at 100 mg/g, taken topical. Manufactured by Chiesi USA, Inc..

Key Facts

Brand Name
FILSUVEZ
Generic Name
birch triterpenes
NDC Code (Product)
10122-310
Manufacturer
Chiesi USA, Inc.
Strength
100 mg/g
Dosage Form
GEL
Route
TOPICAL
Marketing Status
Application #
NDA215064
Marketing Start
02/22/2024

Recall History

No Recall History

Side Effects Reported to FDA

FDA FAERS database · These are reported events, not confirmed side effects

wound complication30 reports
wound19 reports
drug ineffective17 reports
product dose omission issue12 reports
wound infection12 reports
ill-defined disorder11 reports
wrong technique in product usage process11 reports
blister10 reports
product administration interrupted10 reports
pruritus10 reports

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

1 INDICATIONS AND USAGE FILSUVEZ is indicated for the treatment of wounds associated with dystrophic and junctional epidermolysis bullosa (EB) in adult and pediatric patients 6 months of age and older. FILSUVEZ topical gel is indicated for the treatment of wounds associated with dystrophic and junctional epidermolysis bullosa in adult and pediatric patients 6 months of age and older. ( 1 )

Dosage & Administration

2 DOSAGE AND ADMINISTRATION Wash hands before and after applying FILSUVEZ or wear gloves for application. Apply a 1 mm layer of FILSUVEZ to the affected wound surface only. Do not rub in the gel. Cover the wound with a sterile non-adhesive wound dressing. Alternatively, apply FILSUVEZ directly to the dressing so that the topical gel is in direct contact with the wound. Apply FILSUVEZ to cleansed wounds with wound dressing changes until the wound is healed. If a FILSUVEZ-treated wound becomes infected, discontinue treatment to that wound until the infection has resolved. Each tube of FILSUVEZ is for one-time use only. Once the tube is opened, use the product immediately. Discard the tube after use in household trash or through a drug take back site, if available. Avoid contact of FILSUVEZ with eyes and mucous membranes (e.g., mouth, vagina, anus). In case of accidental contact, irrigate the area with water. FILSUVEZ is for topical use only. Not for use on mucous membranes (oral, intravaginal, or intra-anal). Not for ophthalmic use. Apply a 1 mm layer of FILSUVEZ to the affected wound surface and cover with wound dressing or apply FILSUVEZ directly to dressing so that the topical gel

Contraindications

4 CONTRAINDICATIONS None. None ( 4 )

Adverse Reactions

6 ADVERSE REACTIONS The following clinically significant adverse reactions are discussed elsewhere in the labeling: Hypersensitivity Reactions [see Warnings and Precautions (5.1) ] The most common (incidence ≥2%) adverse reactions are application site reactions. ( 6.1 ) To report SUSPECTED ADVERSE REACTIONS, contact Chiesi USA Inc. at 1-888-661-9260 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. 6.1 Clinical Trials Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. The safety of FILSUVEZ was evaluated in EASE, a randomized, double-blind, multicenter, placebo-controlled trial in 223 adult and pediatric subjects with inherited EB. During the double-blind phase of EASE, subjects received topical treatment with either FILSUVEZ or a placebo gel on partial-thickness wounds every 1 to 4 days for a total of 90 days. Treated wounds were covered with non-adhesive dressings. Following completion of the double-blind phase, all subjects received FILSUVEZ for a total of 24

Frequently Asked Questions

What is FILSUVEZ used for?

FILSUVEZ contains birch triterpenes. It is a gel taken topical. Consult your doctor for specific uses.

Is FILSUVEZ a controlled substance?

FILSUVEZ is not classified as a controlled substance by the DEA.

What is the generic name for FILSUVEZ?

The generic name for FILSUVEZ is birch triterpenes. There are no other listed brand versions of birch triterpenes.

What is the NDC code for FILSUVEZ 100 mg/g?

The NDC (National Drug Code) for FILSUVEZ 100 mg/g is 10122-310, listed by Chiesi USA, Inc..

Product NDC

10122-310

Package NDC

10122-310-02

Other FILSUVEZ Dosages

Not medical advice. Always consult your doctor or pharmacist before making any medication decisions.

Data from openFDA · Public domain (CC0 1.0)