Drugplain

Dextrose 20 g/100mL

dextrose · INJECTION, SOLUTION · ICU Medical Inc.

10 Recalls on RecordCurrently in Shortage
Plain English

Dextrose is a injection, solution containing dextrose at 20 g/100mL, taken intravenous. Manufactured by ICU Medical Inc..

Key Facts

Brand Name
Dextrose
Generic Name
dextrose
NDC Code (Product)
0990-7935
Manufacturer
ICU Medical Inc.
Strength
20 g/100mL
Dosage Form
INJECTION, SOLUTION
Route
INTRAVENOUS
Marketing Status
Application #
NDA018564
Marketing Start
10/01/2019

Recall History

10 Recalls on Record
Class II08/17/2023

Central Admixture Pharmacy Services, Inc.

Lack of Assurance of Sterility:Lack of validation data for sanitization cycles

TerminatedVoluntary: Firm initiated
Class II04/20/2016

Pharmakon Pharmaceuticals, Inc.

Lack of Assurance of Sterility

TerminatedVoluntary: Firm initiated
Class II09/01/2017

Pharmedium Services, LLC

Subpotent Drug

TerminatedVoluntary: Firm initiated
Class II07/09/2019

Pfizer Inc.

Lack of Assurance of Sterility: Bags have the potential to leak.

TerminatedVoluntary: Firm initiated
Class II04/13/2022

Mckesson Medical-Surgical Inc. Corporate Office

cGMP deviations: Temperature abuse

TerminatedVoluntary: Firm initiated
Class II07/14/2023

Central Admixture Pharmacy Services, Inc.

Lack of assurance of sterility. Validation data for decontamination cycles is lacking.

TerminatedVoluntary: Firm initiated
Class II04/28/2023

Central Admixture Pharmacy Services, Inc.

Lack of Assurance of Sterility: after an FDA inspection called into question the sterility of the products intended to be sterile.

TerminatedVoluntary: Firm initiated
Class II08/10/2017

SSM Health Care St. Louis DBA SSM St. Clare Health Center

Lack of sterility assurance: Microbial growth detected during a routine simulation of the manufacturing process. No batches of distributed product have been identified as actually containing microorganisms.

TerminatedVoluntary: Firm initiated
Class I03/14/2013

Med Prep Consulting, Inc.

Non-Sterility; mold contamination

TerminatedVoluntary: Firm initiated
Class II04/14/2021

Fresenius Medical Care, North America

Labeling; Label Mix-up; 4.25% DEXTROSE bag was found inside a 1.5% DEXTROSE box.

TerminatedVoluntary: Firm initiated

Side Effects Reported to FDA

FDA FAERS database · These are reported events, not confirmed side effects

drug ineffective13,065 reports
off label use11,060 reports
nausea9,935 reports
dyspnoea9,790 reports
pain8,769 reports
diarrhoea8,762 reports
fatigue8,720 reports
pyrexia7,950 reports
acute kidney injury7,860 reports
vomiting7,534 reports

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

1 INDICATIONS AND USAGE ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A is an anticoagulant intended for use only with devices that prepare Platelet Rich Plasma (PRP) products for extracorporeal use. [See Dosage and Administration (2) .] ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A is an anticoagulant intended for use only with devices that prepare Platelet Rich Plasma (PRP) products for extracorporeal use. See the device operator's manual for additional information and complete usage instructions. ( 1 )

Dosage & Administration

2 DOSAGE AND ADMINISTRATION ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A is added to blood products collected for extracorporeal processing. ( 2 ) ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A may only be used with devices that prepare Platelet Rich Plasma (PRP) products for extracorporeal use. For instructions on the use of the solution see the device operator's manual. ( 2.1 ) Follow the directions for drawing ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A into a syringe for further processing of the collected blood product. ( 2.2 ) 2.1 General Dosing Information ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A is added to blood products collected for extracorporeal processing. The solution is manually added to collected blood products to facilitate extracorporeal processing. The amount of solution added is specified by the manufacturer of the processing set. It is not intended for direct intravenous infusion. For instructions on the use of the solution with the processing set, see the device operator's manual. 2.2 Administration Ensure solution is the ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A and is with

Contraindications

4 CONTRAINDICATIONS NOT FOR PREPARATION OF BLOOD PRODUCTS FOR TRANSFUSION OR FOR DIRECT INTRAVENOUS INFUSION. NOT FOR PREPARATION OF BLOOD PRODUCTS FOR TRANSFUSION OR FOR DIRECT INTRAVENOUS INFUSION. ( 4 )

Adverse Reactions

6 ADVERSE REACTIONS Citrate reactions or toxicity may occur with the injection of blood products containing citrate anticoagulant. The recipient of the blood product containing citrate should be monitored for the signs and symptoms of citrate toxicity. The signs and symptoms of citrate toxicity begin with paresthesia, a "tingling" sensation around the mouth or in the extremities, followed by severe reactions that are characterized by hypotension and possible cardiac arrhythmia. Citrate toxicity may occur more frequently in patients who are hypothermic, have impaired liver or renal function, or have low calcium levels because of an underlying disease. Citrate reactions or toxicity may occur with the injection of blood products containing citrate anticoagulant. The recipient of the blood product containing citrate should be monitored for the signs and symptoms of citrate toxicity. ( 6 ) To report SUSPECTED ADVERSE REACTIONS, contact Terumo BCT, Inc. at 1-877-339-4228 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch .

Frequently Asked Questions

What is Dextrose used for?

Dextrose contains dextrose. It is a injection, solution taken intravenous. Consult your doctor for specific uses.

Is Dextrose a controlled substance?

Dextrose is not classified as a controlled substance by the DEA.

What is the generic name for Dextrose?

The generic name for Dextrose is dextrose. There are 10 other brand versions of dextrose.

What is the NDC code for Dextrose 20 g/100mL?

The NDC (National Drug Code) for Dextrose 20 g/100mL is 0990-7935, listed by ICU Medical Inc..