Drugplain

Desoximetasone 2.5 mg/mL

Desoximetasone · SPRAY · Lupin Pharmaceuticals, Inc.

10 Recalls on Record
Plain English

Desoximetasone is a spray containing desoximetasone at 2.5 mg/mL, taken topical. Manufactured by Lupin Pharmaceuticals, Inc..

Key Facts

Brand Name
Desoximetasone
Generic Name
Desoximetasone
NDC Code (Product)
68180-944
Manufacturer
Lupin Pharmaceuticals, Inc.
Strength
2.5 mg/mL
Dosage Form
SPRAY
Route
TOPICAL
Marketing Status
Application #
ANDA208124
Drug Class
Corticosteroid [EPC]
Marketing Start
07/20/2018

Recall History

10 Recalls on Record
Class II11/14/2016

Akorn Inc

Failed Stability Specifications; out-of specification value for homogeneity / phase separation.

TerminatedVoluntary: Firm initiated
Class II09/13/2016

Taro Pharmaceuticals, Inc.

Failed Stability Specifications: The subject lots exhibited OOS results for Homogeneity test (Moderate separation).

TerminatedVoluntary: Firm initiated
Class II03/15/2022

Teligent Pharma, Inc.

cGMP deviations: all products within expiry are being recalled because the firm is discontinuing its stability study program.

TerminatedVoluntary: Firm initiated
Class II11/14/2014

Attix Pharmaceuticals

Penicillin Cross Contamination: All lots of all products repackaged and distributed between 01/05/12 and 02/12/15 are being recalled because they were repackaged in a facility with penicillin products without adequate separation which could introduce the potential for cross contamination with penicillin.

TerminatedVoluntary: Firm initiated
Class II02/09/2018

American Pharmaceutical Ingredients LLC

CGMP Deviations: Lack of stability data and controls to support the manufacturers assigned retest or expiration date in firm's container/closure system.

TerminatedVoluntary: Firm initiated
Class II09/13/2016

Taro Pharmaceuticals, Inc.

Failed Stability Specifications: The subject lots exhibited OOS results for Homogeneity test (Moderate separation).

TerminatedVoluntary: Firm initiated
Class II02/19/2020

Lupin Pharmaceuticals Inc.

Failed Impurities/Degradation Specification; high out of specification results observed

TerminatedVoluntary: Firm initiated
Class II03/15/2022

Teligent Pharma, Inc.

cGMP deviations: all products within expiry are being recalled because the firm is discontinuing its stability study program.

TerminatedVoluntary: Firm initiated
Class III04/07/2017

Teligent, Inc.

Superpotent Drug

TerminatedVoluntary: Firm initiated
Class II03/15/2022

Teligent Pharma, Inc.

cGMP deviations: all products within expiry are being recalled because the firm is discontinuing its stability study program.

TerminatedVoluntary: Firm initiated

Side Effects Reported to FDA

FDA FAERS database · These are reported events, not confirmed side effects

drug ineffective9,688 reports
pain8,711 reports
fatigue8,553 reports
rheumatoid arthritis8,029 reports
alopecia7,984 reports
systemic lupus erythematosus7,837 reports
abdominal discomfort7,613 reports
pemphigus7,601 reports
glossodynia7,394 reports
swelling6,934 reports

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

INDICATIONS AND USAGE Desoximetasone cream USP, 0.05%, desoximetasone cream USP, 0.25%, and desoximetasone gel USP, 0.05% are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Dosage & Administration

DOSAGE AND ADMINISTRATION Apply a thin film of desoximetasone cream USP, 0.05%, desoximetasone cream USP, 0.25%, or desoximetasone gel USP, 0.05% to the affected skin areas twice daily. Rub in gently.

Warnings

WARNINGS Keep out of reach of children.

Contraindications

CONTRAINDICATIONS Desoximetasone cream USP, 0.05%, desoximetasone cream USP, 0.25%, and desoximetasone gel USP, 0.05% are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.

Adverse Reactions

ADVERSE REACTIONS The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: Burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, and miliaria. In controlled clinical studies the incidence of adverse reactions were low (0.8%) for desoximetasone cream USP, 0.25%, and included burning, folliculitis, and folliculo-pustular lesions. The incidence of adverse reactions were also 0.8% for desoximetasone cream USP, 0.05% and included pruritus, erythema, vesiculation, and burning sensation. The incidence of adverse reactions for desoximetasone gel USP, 0.05% was 0.3% with one subject reporting stinging and burning at the site of application.

Frequently Asked Questions

What is Desoximetasone used for?

Desoximetasone contains Desoximetasone. It is a spray taken topical. Consult your doctor for specific uses.

Is Desoximetasone a controlled substance?

Desoximetasone is not classified as a controlled substance by the DEA.

What is the generic name for Desoximetasone?

The generic name for Desoximetasone is Desoximetasone. There are 6 other brand versions of Desoximetasone.

What is the NDC code for Desoximetasone 2.5 mg/mL?

The NDC (National Drug Code) for Desoximetasone 2.5 mg/mL is 68180-944, listed by Lupin Pharmaceuticals, Inc..