Drugplain

DERMA-SMOOTHE/FS .11 mg/mL

fluocinolone acetonide · OIL · Royal Pharmaceuticals

10 Recalls on Record
Plain English

DERMA-SMOOTHE/FS is a oil containing fluocinolone acetonide at .11 mg/mL, taken topical. Manufactured by Royal Pharmaceuticals.

Key Facts

Brand Name
DERMA-SMOOTHE/FS
Generic Name
fluocinolone acetonide
NDC Code (Product)
68791-102
Manufacturer
Royal Pharmaceuticals
Strength
.11 mg/mL
Dosage Form
OIL
Route
TOPICAL
Marketing Status
Application #
NDA019452
Drug Class
Corticosteroid [EPC]
Marketing Start
02/16/1995

Recall History

10 Recalls on Record
Class III05/08/2012

Hill Dermaceuticals, Inc.

Subpotent; fluocinolone acetonide

TerminatedVoluntary: Firm initiated
Class III01/31/2014

Hill Dermaceuticals, Inc.

Subpotent Drug: The active ingredient, fluocinolone acetonide, was found to be subpotent during the firm's routine testing.

TerminatedVoluntary: Firm initiated
Class III11/21/2012

Hill Dermaceuticals, Inc.

Subpotent; 22 month stability timepoint

TerminatedVoluntary: Firm initiated
Class III09/08/2013

Hill Dermaceuticals, Inc.

Subpotent Drug: The active ingredient, fluocinolone acetonide, was found to be subpotent during the firm's routine testing.

TerminatedVoluntary: Firm initiated
Class III09/08/2013

Hill Dermaceuticals, Inc.

Subpotent Drug: The active ingredient, fluocinolone acetonide, was found to be subpotent during the firm's routine testing.

TerminatedVoluntary: Firm initiated
Class III01/31/2014

Hill Dermaceuticals, Inc.

Subpotent Drug: The active ingredient, fluocinolone acetonide, was found to be subpotent during the firm's routine testing.

TerminatedVoluntary: Firm initiated
Class III05/08/2012

Hill Dermaceuticals, Inc.

Subpotent; fluocinolone acetonide

TerminatedVoluntary: Firm initiated
Class III11/21/2012

Hill Dermaceuticals, Inc.

Subpotent; 12 month stability timepoint

TerminatedVoluntary: Firm initiated
Class III01/31/2014

Hill Dermaceuticals, Inc.

Subpotent Drug: The active ingredient, fluocinolone acetonide, was found to be subpotent during the firm's routine testing.

TerminatedVoluntary: Firm initiated
Class III01/31/2014

Hill Dermaceuticals, Inc.

Subpotent Drug: The active ingredient, fluocinolone acetonide, was found to be subpotent during the firm's routine testing.

TerminatedVoluntary: Firm initiated

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

1 INDICATIONS AND USAGE Derma-Smoothe/FS ® Scalp Oil is a corticosteroid indicated for the treatment of psoriasis of the scalp in adults. ( 1 ) DERMA-SMOOTHE/FS ® Scalp Oil is indicated for the treatment of psoriasis of the scalp in adults.

Dosage & Administration

2 DOSAGE AND ADMINISTRATION DERMA-SMOOTHE/FS Scalp Oil is for topical use only. Not for oral, ophthalmic, or intravaginal use. Wet or dampen hair and scalp thoroughly. Apply a thin film of DERMA-SMOOTHE/FS Scalp Oil on the scalp, massage well and cover scalp with the supplied shower cap. Leave on overnight or for a minimum of 4 hours then wash hair with regular shampoo and rinse thoroughly. Use daily as needed. Discontinue DERMA-SMOOTHE/FS Scalp Oil when control of disease is achieved within 2 weeks, or contact the healthcare provider if no improvement is seen within 2 weeks. Do not use DERMA-SMOOTHE/FS Scalp Oil on the face unless directed by the healthcare provider. Do not apply to intertriginous areas due to the increased risk of local adverse reactions [see Adverse Reactions (6) ] . Do not apply to the diaper area; diapers or plastic pants may constitute occlusive use. [see Warnings and Precautions (5.1) ] DERMA-SMOOTHE/FS Scalp Oil is not for oral, ophthalmic, or intravaginal use. ( 2 ) Do not use on face or intertriginous areas. ( 2 ) Apply a thin film of DERMA-SMOOTHE/FS Scalp Oil on the wet scalp, massage well and cover scalp with the supplied shower cap. Leave on overnight

Contraindications

4 CONTRAINDICATIONS None. None. ( 4 )

Adverse Reactions

6 ADVERSE REACTIONS The following serious adverse reactions are discussed in more detail in other sections of the labeling: • Endocrine System Adverse Reactions [see Warnings and Precautions (5.1) ] • Local Adverse Reactions [see Warnings and Precautions (5.2) ] • Ophthalmic Adverse Reactions [see Warnings and Precautions (5.3) ] The most common adverse reactions in pediatric subjects treated for atopic dermatitis (≥5%) were cough (20%), rhinorrhea (13%), pyrexia (10%), telangiectasia (7%), nasopharyngitis (7%), and hypopigmentation (7%). ( 6.1 , 6.2 ) To report SUSPECTED ADVERSE REACTIONS, contact Hill Dermaceuticals, Inc. at 1-800-344-5707 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. 6.1 Clinical Studies Experience Because clinical trials are conducted under widely varying condition, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. An open-label safety study was conducted in 29 pediatric subjects 3 months to 2 years old to assess the HPA axis by ACTH stimulation testing following use of the formulation of DERMA-SMOOTHE/FS Scalp Oil t

Frequently Asked Questions

What is DERMA-SMOOTHE/FS used for?

DERMA-SMOOTHE/FS contains fluocinolone acetonide. It is a oil taken topical. Consult your doctor for specific uses.

Is DERMA-SMOOTHE/FS a controlled substance?

DERMA-SMOOTHE/FS is not classified as a controlled substance by the DEA.

What is the generic name for DERMA-SMOOTHE/FS?

The generic name for DERMA-SMOOTHE/FS is fluocinolone acetonide. There are 12 other brand versions of fluocinolone acetonide.

What is the NDC code for DERMA-SMOOTHE/FS .11 mg/mL?

The NDC (National Drug Code) for DERMA-SMOOTHE/FS .11 mg/mL is 68791-102, listed by Royal Pharmaceuticals.