Drugplain

Cyclopentolate Hydrochloride 10 mg/mL

Cyclopentolate Hydrochloride · SOLUTION · Sandoz Inc.

1 Recall on Record
Plain English

Cyclopentolate Hydrochloride is a solution containing cyclopentolate hydrochloride at 10 mg/mL, taken ophthalmic. Manufactured by Sandoz Inc..

Key Facts

Brand Name
Cyclopentolate Hydrochloride
Generic Name
Cyclopentolate Hydrochloride
NDC Code (Product)
61314-396
Manufacturer
Sandoz Inc.
Strength
10 mg/mL
Dosage Form
SOLUTION
Route
OPHTHALMIC
Marketing Status
Application #
ANDA084110
Marketing Start
08/22/2002

Recall History

1 Recall on Record
Class III01/18/2016

Bausch & Lomb, Inc.

Labeling: Incorrect or Missing Package Insert: Package insert is missing updates compared with reference drug insert.

TerminatedVoluntary: Firm initiated

Side Effects Reported to FDA

FDA FAERS database · These are reported events, not confirmed side effects

dizziness32 reports
eye pain28 reports
keratopathy26 reports
nausea25 reports
headache24 reports
back pain19 reports
toxic anterior segment syndrome19 reports
drug ineffective17 reports
dyspnoea17 reports
diarrhoea16 reports

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

INDICATIONS AND USAGE Cyclopentolate hydrochloride ophthalmic solution is used to produce mydriasis and cycloplegia.

Dosage & Administration

DOSAGE AND ADMINISTRATION Adults: Instill one or two drops of 1% solution in the eye which may be repeated in five to ten minutes if necessary. Complete recovery usually occurs in 24 hours. Complete recovery from mydriasis in some individuals may require several days. Children: Instill one or two drops of 1% solution in the eye, which may be repeated five to ten minutes later by a second application of 1% solution if necessary. Individuals with heavily pigmented irides may require higher strengths.

Warnings

WARNINGS FOR TOPICAL OPHTHALMIC USE. NOT FOR INJECTION. This preparation may cause Central Nervous System (CNS) disturbances. This is especially true in younger age groups, but may occur at any age, especially with the stronger cyclopentolate hydrochloride solutions. Infants are especially prone to CNS and cardiopulmonary side effects from cyclopentolate. To minimize absorption, use only 1 drop of a 1% cyclopentolate solution per eye, followed by pressure applied over the nasolacrimal sac for two to three minutes. Observe infants closely for at least 30 minutes following instillation. Mydriatics may produce a transient elevation of intraocular pressure.

Contraindications

CONTRAINDICATIONS Hypersensitive to any component of this preparation.

Drug Interactions

Drug Interactions: Cyclopentolate may interfere with the ocular anti-hypertensive action of carbachol, pilocarpine, or ophthalmic cholinesterase inhibitors.

Adverse Reactions

ADVERSE REACTIONS Ocular: Increased intraocular pressure, burning, photophobia, blurred vision, irritation, hyperemia, conjunctivitis, blepharoconjunctivitis, punctate keratitis, synechiae have been reported. Non-ocular: Use of cyclopentolate has been associated with psychotic reactions and behavioral disturbances, usually in children, especially with 2% concentration. These disturbances include ataxia, incoherent speech, restlessness, hallucinations, hyperactivity, seizures, disorientation as to time and place, and failure to recognize people. This drug produces reactions similar to those of other anticholinergic drugs, but the CNS manifestations as noted above are more common. Other toxic manifestations of anticholinergic drugs are skin rash, abdominal distention in infants, necrotizing enterocolitis (in preterm infants), unusual drowsiness, tachycardia, hyperpyrexia, vasodilation, urinary retention, diminished gastrointestinal motility and decreased secretion in salivary and sweat glands, pharynx, bronchi and nasal passages. Severe manifestations of toxicity include coma, medullary paralysis and death. To report SUSPECTED ADVERSE REACTIONS, contact Bausch & Lomb Incorporated at

Frequently Asked Questions

What is Cyclopentolate Hydrochloride used for?

Cyclopentolate Hydrochloride contains Cyclopentolate Hydrochloride. It is a solution taken ophthalmic. Consult your doctor for specific uses.

Is Cyclopentolate Hydrochloride a controlled substance?

Cyclopentolate Hydrochloride is not classified as a controlled substance by the DEA.

What is the generic name for Cyclopentolate Hydrochloride?

The generic name for Cyclopentolate Hydrochloride is Cyclopentolate Hydrochloride. There are 4 other brand versions of Cyclopentolate Hydrochloride.

What is the NDC code for Cyclopentolate Hydrochloride 10 mg/mL?

The NDC (National Drug Code) for Cyclopentolate Hydrochloride 10 mg/mL is 61314-396, listed by Sandoz Inc..

Product NDC

61314-396

Package NDC

61314-396-01

Other Cyclopentolate Hydrochloride Dosages

Not medical advice. Always consult your doctor or pharmacist before making any medication decisions.

Data from openFDA · Public domain (CC0 1.0)