Compro 25 mg/1
PROCHLORPERAZINE · SUPPOSITORY · PD-Rx Pharmaceuticals, Inc.
Compro is a suppository containing prochlorperazine at 25 mg/1, taken rectal. Manufactured by PD-Rx Pharmaceuticals, Inc..
Key Facts
- Brand Name
- Compro
- Generic Name
- PROCHLORPERAZINE
- NDC Code (Product)
55289-119- Manufacturer
- PD-Rx Pharmaceuticals, Inc.
- Strength
- 25 mg/1
- Dosage Form
- SUPPOSITORY
- Route
- RECTAL
- Marketing Status
- Application #
- ANDA040246
- Drug Class
- Phenothiazine [EPC]
- Marketing Start
- 09/01/2000
Recall History
No Recall HistoryFull Prescribing Information
Indications & Usage
INDICATIONS AND USAGE Prochlorperazine 25 mg suppositories are indicated in the control of severe nausea and vomiting in adults.
Dosage & Administration
DOSAGE AND ADMINISTRATION Adults: Dosage should be increased more gradually in debilitated or emaciated patients. Elderly Patients: In general, dosages in the lower range are sufficient for most elderly patients. Since they appear to be more susceptible to hypotension and neuromuscular reactions, such patients should be observed closely. Dosage should be tailored to the individual, response carefully monitored and dosage adjusted accordingly. Dosage should be increased more gradually in elderly patients. To Control Severe Nausea and Vomiting: Adjust dosage to the response of the individual. Begin with the lowest recommended dosage. Rectal Dosage: 25 mg twice daily.
Warnings
WARNINGS Increased Mortality in Elderly Patients with Dementia-Related Psychosis Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Compro ® Prochlorperazine Suppositories USP is not approved for the treatment of patients with dementia-related psychosis (see BOXED WARNING ). The extrapyramidal symptoms which can occur secondary to prochlorperazine may be confused with the central nervous system signs of an undiagnosed primary disease responsible for the vomiting, e.g., Reye's Syndrome or other encephalopathy. The use of prochlorperazine and other potential hepatotoxins should be avoided in children and adolescents whose signs and symptoms suggest Reye's Syndrome. Tardive Dyskinesia: Tardive dyskinesia, a syndrome consisting of potentially irreversible, involuntary, dyskinetic movements, may develop in patients treated with neuroleptic (antipsychotic) drugs. Although the prevalence of the syndrome appears to be highest among the elderly, especially elderly women, it is impossible to rely upon prevalence estimates to predict, at the inception of neuroleptic treatment, which patients are likely to develop the syndrome. …
Contraindications
CONTRAINDICATIONS Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. Do not use in children under 2 years of age or under 20 lbs. Do not use in children for conditions for which dosage has not been established.
Adverse Reactions
ADVERSE REACTIONS Drowsiness, dizziness, amenorrhea, blurred vision, skin reactions and hypotension may occur. Cholestatic jaundice has occurred. If fever with grippe-like symptoms occurs, appropriate liver studies should be conducted. If tests indicate an abnormality, stop treatment. There have been a few observations of fatty changes in the livers of patients who have died while receiving the drug. No causal relationship has been established. Leukopenia and agranulocytosis have occurred. Warn patients to report the sudden appearance of sore throat or other signs of infection. If white blood cell and differential counts indicate leukocyte depression, stop treatment and start antibiotic and other suitable therapy. Neuromuscular (Extrapyramidal) Reactions These symptoms are seen in a significant number of hospitalized mental patients. They may be characterized by motor restlessness, be of the dystonic type, or they may resemble parkinsonism. Depending on the severity of symptoms, dosage should be reduced or discontinued. If therapy is reinstituted, it should be at a lower dosage. Should these symptoms occur in children or pregnant patients, the drug should be stopped and not reinsti…
Frequently Asked Questions
What is Compro used for?
Compro contains PROCHLORPERAZINE. It is a suppository taken rectal. Consult your doctor for specific uses.
Is Compro a controlled substance?
Compro is not classified as a controlled substance by the DEA.
What is the generic name for Compro?
The generic name for Compro is PROCHLORPERAZINE. There are 12 other brand versions of PROCHLORPERAZINE.
What is the NDC code for Compro 25 mg/1?
The NDC (National Drug Code) for Compro 25 mg/1 is 55289-119, listed by PD-Rx Pharmaceuticals, Inc..
Other Prochlorperazine Brands
See all →- Prochlorperazine Edisylate5 mg/mL72266-204
- Prochlorperazine Edisylate5 mg/mL72572-580
- Prochlorperazine Edisylate5 mg/mL0641-6135
- Prochlorperazine Edisylate5 mg/mL23155-523
- PROCHLORPERAZINE MALEATE10 mg/142708-103
- PROCHLORPERAZINE MALEATE10 mg/150090-2839
- PROCHLORPERAZINE MALEATE10 mg/159746-115
- PROCHLORPERAZINE MALEATE5 mg/167296-2099
- Prochlorperazine Maleate10 mg/170518-4319
- Prochlorperazine Maleate10 mg/170954-689
Not medical advice. Always consult your doctor or pharmacist before making any medication decisions.
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