Drugplain

ChloraPrep One-Step 20 mg/mL

chlorhexidine gluconate and isopropyl alcohol · SOLUTION · CareFusion 213, LLC

4 Recalls on Record
Plain English

ChloraPrep One-Step is a prescription solution containing chlorhexidine gluconate and isopropyl alcohol at 20 mg/mL, taken topical. Manufactured by CareFusion 213, LLC.

Key Facts

Brand Name
ChloraPrep One-Step
Generic Name
chlorhexidine gluconate and isopropyl alcohol
NDC Code (Product)
54365-400
Manufacturer
CareFusion 213, LLC
Strength
20 mg/mL
Dosage Form
SOLUTION
Route
TOPICAL
Marketing Status
HUMAN OTC DRUG
Application #
NDA020832
Drug Class
Decreased Cell Wall Integrity [PE]
Marketing Start
05/24/2019

Recall History

4 Recalls on Record
Class I03/19/2021

CareFusion 213, LLC

Microbial Contamination of Non-Sterile Product.Product is being recalled because at labeled storage conditions of 30*C/75% Relative Humidity, growth of Aspergillus penicillioides, a type of fungus, resulted in a breach of the package integrity.

TerminatedVoluntary: Firm initiated
Class II04/23/2012

Carefusion 213, Llc

Lack of Assurance of Sterility: Firm mistakenly released quarantined, non conforming material that failed sterility testing.

TerminatedVoluntary: Firm initiated
Class II03/19/2021

CareFusion 213, LLC

CGMP Deviations: Product is being recalled because at labeled storage conditions of 30*C/75% Relative Humidity, there is the potential for growth of Aspergillus penicillioides, a type of fungus, resulting in a breach of the package integrity.

TerminatedVoluntary: Firm initiated
Class I07/07/2020

CareFusion 213, LLC

Microbial Contamination of Non-Sterile Product: Product is being recalled to climatic Zone IV regions of the world where at the labeled storage conditions of 30*C/75% Relative Humidity for more than 6 months, there is the potential for growth of Aspergillus penicillioides, a type of fungus, resulting in a breach of the package integrity.

TerminatedVoluntary: Firm initiated

Side Effects Reported to FDA

FDA FAERS database · These are reported events, not confirmed side effects

sinusitis210 reports
pain206 reports
lower respiratory tract infection204 reports
pruritus191 reports
rash186 reports
joint swelling185 reports
peripheral swelling181 reports
insomnia179 reports
impaired healing155 reports
weight increased155 reports

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

Use for the preparation of the patient’s skin prior to surgery. Helps to reduce bacteria that potentially can cause skin infection.

Dosage & Administration

Directions • use with care in premature infants or infants under 2 months of age. These products may cause irritation or chemical burns. • maximal treatment area for one applicator is approximately 2.5 in. x 2.5 in. (42 cm 2 ) • remove applicator from package; do not touch sponge • hold the applicator horizontally with the sponge down. Pinch wings only once to activate the ampule and release the antiseptic. • wet the sponge by pressing and releasing the sponge against the treatment area until liquid is visible on the skin • completely wet the treatment area with antiseptic • dry surgical sites (e.g., abdomen or arm): use gentle repeated back-and-forth strokes for 30 seconds. Allow the area to air dry for approximately 30 seconds. • moist surgical sites (e.g., inguinal fold): use gentle repeated back-and-forth strokes for 2 minutes. Allow the area to air dry for approximately 1 minute. • do not blot or wipe away • discard the applicator after a single use along with any portion of the solution not required to cover the prep area. It is not necessary to use the entire amount available.

Warnings

Warnings For external use only. Flammable, keep away from fire or flame. • do not use with electrocautery procedures

Frequently Asked Questions

What is ChloraPrep One-Step used for?

ChloraPrep One-Step contains chlorhexidine gluconate and isopropyl alcohol. It is a solution taken topical. Consult your doctor for specific uses.

Is ChloraPrep One-Step a controlled substance?

ChloraPrep One-Step is not classified as a controlled substance by the DEA.

What is the generic name for ChloraPrep One-Step?

The generic name for ChloraPrep One-Step is chlorhexidine gluconate and isopropyl alcohol. There are 6 other brand versions of chlorhexidine gluconate and isopropyl alcohol.

What is the NDC code for ChloraPrep One-Step 20 mg/mL?

The NDC (National Drug Code) for ChloraPrep One-Step 20 mg/mL is 54365-400, listed by CareFusion 213, LLC.

Product NDC

54365-400

Package NDC

54365-400-38

Not medical advice. Always consult your doctor or pharmacist before making any medication decisions.

Data from openFDA · Public domain (CC0 1.0)