Drugplain

BUTAL/APAP/CAFFEINE 325 mg/1

BUTAL/APAP/CAFFEINE · TABLET · Direct_Rx

No Recall History
Plain English

BUTAL/APAP/CAFFEINE is a tablet containing butal/apap/caffeine at 325 mg/1, taken oral. Manufactured by Direct_Rx.

Key Facts

Brand Name
BUTAL/APAP/CAFFEINE
Generic Name
BUTAL/APAP/CAFFEINE
NDC Code (Product)
72189-600
Manufacturer
Direct_Rx
Strength
325 mg/1
Dosage Form
TABLET
Route
ORAL
Marketing Status
DEA Schedule
Schedule III (Controlled)
Application #
ANDA209587
Drug Class
Barbiturate [EPC]; Central Nervous System Stimulant [EPC]
Marketing Start
01/02/2025

Recall History

No Recall History

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

Butalbital, acetaminophen and caffeine tablets are indicated for the relief of the symptom complex of tension (or muscle contraction) headache. Evidence supporting the efficacy and safety of this combination product in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because butalbital is habit-forming and potentially abusable.

Dosage & Administration

One or two tablets every four hours as needed. Total daily dosage should not exceed 6 tablets. Extended and repeated use of this product is not recommended because of the potential for physical dependence.

Warnings

Hepatotoxicity Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 milligrams per day, and often involve more than one acetaminophen-containing product. The excessive intake of acetaminophen may be intentional to cause self-harm or unintentional as patients attempt to obtain more pain relief or unknowingly take other acetaminophen-containing products. The risk of acute liver failure is higher in individuals with underlying liver disease and in individuals who ingest alcohol while taking acetaminophen. Instruct patients to look for acetaminophen or APAP on package labels and not to use more than one product that contains acetaminophen. Instruct patients to seek medical attention immediately upon ingestion of more than 4000 milligrams of acetaminophen per day, even if they feel well. Serious skin reactions Rarely, acetaminophen may cause serious skin reactions such as acute generalized exanthematous pustulosis (AGEP), Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. Patients

Contraindications

This product is contraindicated under the following conditions: – Hypersensitivity or intolerance to any component of this product – Patients with porphyria.

Adverse Reactions

Frequently Observed The most frequently reported adverse reactions are drowsiness, lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting, abdominal pain, and intoxicated feeling. Infrequently Observed All adverse events tabulated below are classified as infrequent. Central Nervous System: headache, shaky feeling, tingling, agitation, fainting, fatigue, heavy eyelids, high energy, hot spells, numbness, sluggishness, seizure. Mental confusion, excitement, or depression can also occur due to intolerance, particularly in elderly or debilitated patients, or due to overdosage of butalbital. Autonomic Nervous System: dry mouth, hyperhidrosis. Gastrointestinal: difficulty swallowing, heartburn, flatulence, constipation. Cardiovascular: tachycardia. Musculoskeletal: leg pain, muscle fatigue. Genitourinary: diuresis. Miscellaneous: pruritus, fever, earache, nasal congestion, tinnitus, euphoria, allergic reactions. Several cases of dermatological reactions, including toxic epidermal necrolysis and erythema multiforme, have been reported. The following adverse drug events may be borne in mind as potential effects of the components of this product. Potential effects of hig

Frequently Asked Questions

What is BUTAL/APAP/CAFFEINE used for?

BUTAL/APAP/CAFFEINE contains BUTAL/APAP/CAFFEINE. It is a tablet taken oral. Consult your doctor for specific uses.

Is BUTAL/APAP/CAFFEINE a controlled substance?

Yes, BUTAL/APAP/CAFFEINE is classified as CIII under the DEA Controlled Substances Act.

What is the generic name for BUTAL/APAP/CAFFEINE?

The generic name for BUTAL/APAP/CAFFEINE is BUTAL/APAP/CAFFEINE. There are no other listed brand versions of BUTAL/APAP/CAFFEINE.

What is the NDC code for BUTAL/APAP/CAFFEINE 325 mg/1?

The NDC (National Drug Code) for BUTAL/APAP/CAFFEINE 325 mg/1 is 72189-600, listed by Direct_Rx.

Product NDC

72189-600

Package NDC

72189-600-12

Not medical advice. Always consult your doctor or pharmacist before making any medication decisions.

Data from openFDA · Public domain (CC0 1.0)