Drugplain

BiEST 5.0 Estrogen Cream 1 mg/85g

estriol,estradiol · CREAM · SHYNE BRANDS

No Recall History
Plain English

BiEST 5.0 Estrogen Cream is a cream containing estriol,estradiol at 1 mg/85g, taken transdermal. Manufactured by SHYNE BRANDS.

Key Facts

Brand Name
BiEST 5.0 Estrogen Cream
Generic Name
estriol,estradiol
NDC Code (Product)
82018-0009
Manufacturer
SHYNE BRANDS
Strength
1 mg/85g
Dosage Form
CREAM
Route
TRANSDERMAL
Marketing Status
Drug Class
Estrogen [EPC]
Marketing Start
06/01/2025

Recall History

No Recall History

Side Effects Reported to FDA

FDA FAERS database · These are reported events, not confirmed side effects

fatigue2 reports
pain2 reports
abdominal discomfort1 reports
abdominal pain upper1 reports
alopecia1 reports
amnesia1 reports
angioedema1 reports
anosmia1 reports
anxiety1 reports
arthralgia1 reports

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

USES: This is a topical cream that contains bio-identical estriol and estradiol derived from wild yam and formulated in an 80:20 ratio. When applied to the skin it can help balance your hormones and provide temporary relief from menopausal symptoms such as hot flashes. DIRECTIONS: Apply once or twice a day. Massage into inner arms, thighs, chest or apply to inner forearm and rub arms together or use as directed by your Physician.

Dosage & Administration

Apply once or twice a day. Massage into inner arms, thighs, chest or apply to inner forearm and rub arms together or use as directed by you physician.

Warnings

For external cosmetic use only. If pregnant or nursing, consult a healthcare professional before using this product. Cease using this product and seek medical attention if skin irritation or other negative reactions occur. Do not use if tamper-evident seal is broken or missing. California Prop 65 Law requires this statement: This product contains estrogen, a chemical known only to the state of California to cause cancer. KEEP OUT OF REACH OF CHILDREN.

Frequently Asked Questions

What is BiEST 5.0 Estrogen Cream used for?

BiEST 5.0 Estrogen Cream contains estriol,estradiol. It is a cream taken transdermal. Consult your doctor for specific uses.

Is BiEST 5.0 Estrogen Cream a controlled substance?

BiEST 5.0 Estrogen Cream is not classified as a controlled substance by the DEA.

What is the generic name for BiEST 5.0 Estrogen Cream?

The generic name for BiEST 5.0 Estrogen Cream is estriol,estradiol. There are 3 other brand versions of estriol,estradiol.

What is the NDC code for BiEST 5.0 Estrogen Cream 1 mg/85g?

The NDC (National Drug Code) for BiEST 5.0 Estrogen Cream 1 mg/85g is 82018-0009, listed by SHYNE BRANDS.

Product NDC

82018-0009

Package NDC

82018-0009-3

Not medical advice. Always consult your doctor or pharmacist before making any medication decisions.

Data from openFDA · Public domain (CC0 1.0)