Drugplain

Acetaminophen, Dextromethorphan Hydrobromide and Phenylephrine Hydrochloride 325 mg/1

Acetaminophen, Dextromethorphan Hydrobromide and Phenylephrine Hydrochloride · CAPSULE, LIQUID FILLED · Prodose, Inc.

No Recall HistoryCurrently in Shortage
Plain English

This over-the-counter medication combines three active ingredients to help relieve cold and flu symptoms: acetaminophen reduces fever and pain, dextromethorphan suppresses cough, and phenylephrine relieves nasal congestion. It comes as an oral liquid-filled capsule.

Key Facts

Brand Name
Acetaminophen, Dextromethorphan Hydrobromide and Phenylephrine Hydrochloride
Generic Name
Acetaminophen, Dextromethorphan Hydrobromide and Phenylephrine Hydrochloride
NDC Code (Product)
68210-5053
Manufacturer
Prodose, Inc.
Strength
325 mg/1
Dosage Form
CAPSULE, LIQUID FILLED
Route
ORAL
Marketing Status
HUMAN OTC DRUG
Application #
M012
Drug Class
Adrenergic alpha1-Agonists [MoA]; Sigma-1 Agonist [EPC]
Marketing Start
07/29/2025

Recall History

No Recall History

Side Effects Reported to FDA

FDA FAERS database · These are reported events, not confirmed side effects

aspartate aminotransferase increased1 reports
jaundice1 reports
myocardial infarction1 reports
potentiating drug interaction1 reports
transaminases increased1 reports

Full Prescribing Information

Source: FDA Drug Label (SPL)For healthcare professionals

Indications & Usage

Uses Temporarily relieves common cold/flu symptoms: nasal congestion cough due to minor throat & bronchial irritation sore throat headache minor aches & pains fever

Dosage & Administration

Directions take only as directed do not exceed 8 Softgels per 24 hrs adults & children 12 years & over 2 Softgels with water every 4 hours children 4 to under 12 years ask a doctor children under 4 years do not use

Warnings

Warnings Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take more than 8 Softgels in 24 hrs, which is the maximum daily amount for this product with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy Alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away. Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.

Frequently Asked Questions

What is Acetaminophen, Dextromethorphan Hydrobromide and Phenylephrine Hydrochloride used for?

This over-the-counter medication combines three active ingredients to help relieve cold and flu symptoms: acetaminophen reduces fever and pain, dextromethorphan suppresses cough, and phenylephrine relieves nasal congestion. It comes as an oral liquid-filled capsule.

Is Acetaminophen, Dextromethorphan Hydrobromide and Phenylephrine Hydrochloride a controlled substance?

Acetaminophen, Dextromethorphan Hydrobromide and Phenylephrine Hydrochloride is not classified as a controlled substance by the DEA.

What is the generic name for Acetaminophen, Dextromethorphan Hydrobromide and Phenylephrine Hydrochloride?

The generic name for Acetaminophen, Dextromethorphan Hydrobromide and Phenylephrine Hydrochloride is Acetaminophen, Dextromethorphan Hydrobromide and Phenylephrine Hydrochloride. There are no other listed brand versions of Acetaminophen, Dextromethorphan Hydrobromide and Phenylephrine Hydrochloride.

What is the NDC code for Acetaminophen, Dextromethorphan Hydrobromide and Phenylephrine Hydrochloride 325 mg/1?

The NDC (National Drug Code) for Acetaminophen, Dextromethorphan Hydrobromide and Phenylephrine Hydrochloride 325 mg/1 is 68210-5053, listed by Prodose, Inc..

Product NDC

68210-5053

Package NDC

68210-5053-1

Not medical advice. Always consult your doctor or pharmacist before making any medication decisions.

Data from openFDA · Public domain (CC0 1.0)