Drugplain

Acetaminophen and Diphenhydramine HCL 500 mg/1

Acetaminophen and Diphenhydramine HCL · TABLET · SAFEWAY

No Recall HistoryCurrently in Shortage
Plain English

This over-the-counter tablet combines acetaminophen (a pain reliever and fever reducer) with diphenhydramine (an antihistamine that causes drowsiness) to treat pain, fever, and allergy symptoms. It is commonly used for nighttime relief of cold, flu, and minor ache symptoms when sleep support is needed.

Key Facts

Brand Name
Acetaminophen and Diphenhydramine HCL
Generic Name
Acetaminophen and Diphenhydramine HCL
NDC Code (Product)
21130-661
Manufacturer
SAFEWAY
Strength
500 mg/1
Dosage Form
TABLET
Route
ORAL
Marketing Status
Application #
M013
Drug Class
Histamine-1 Receptor Antagonist [EPC]
Marketing Start
06/30/2023

Recall History

No Recall History

Side Effects Reported to FDA

FDA FAERS database · These are reported events, not confirmed side effects

completed suicide2 reports
toxicity to various agents2 reports
cardiac arrest1 reports
death1 reports
incorrect route of drug administration1 reports
potentiating drug interaction1 reports
respiratory arrest1 reports
self-medication1 reports

Frequently Asked Questions

What is Acetaminophen and Diphenhydramine HCL used for?

This over-the-counter tablet combines acetaminophen (a pain reliever and fever reducer) with diphenhydramine (an antihistamine that causes drowsiness) to treat pain, fever, and allergy symptoms. It is commonly used for nighttime relief of cold, flu, and minor ache symptoms when sleep support is needed.

Is Acetaminophen and Diphenhydramine HCL a controlled substance?

Acetaminophen and Diphenhydramine HCL is not classified as a controlled substance by the DEA.

What is the generic name for Acetaminophen and Diphenhydramine HCL?

The generic name for Acetaminophen and Diphenhydramine HCL is Acetaminophen and Diphenhydramine HCL. There are 6 other brand versions of Acetaminophen and Diphenhydramine HCL.

What is the NDC code for Acetaminophen and Diphenhydramine HCL 500 mg/1?

The NDC (National Drug Code) for Acetaminophen and Diphenhydramine HCL 500 mg/1 is 21130-661, listed by SAFEWAY.

Product NDC

21130-661

Package NDC

21130-661-10

Other Acetaminophen and Diphenhydramine HCL Dosages

Not medical advice. Always consult your doctor or pharmacist before making any medication decisions.

Data from openFDA · Public domain (CC0 1.0)